CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Reliable Proliferation And Differentiation Of Desired T Cell Subpopulations

  This study evaluates a cost-effective alternative to Proleukin® for expanding T cells that demonstrates comparable performance across cell viability, subpopulation ratios, and clinical consistency.

• Streamlining Compliance With Pre-Clinical Safety Tests

  As cell therapies advance, challenges in ensuring safe, scalable, and compliant production increase. Discover how to develop efficient strategies to maintain cell viability and functionality throughout the supply chain.

• Automating High-Throughput Screens Using Patient-Derived Organoids

  Many oncology drugs fail in later development stages due to inadequate predictive models. Explore how 3D cell models, like patient-derived organoids, offer a promising solution in the drug development process.

• Analysis Of Partial Capsids Using Empty-Full Capsid Kit

  Discover how to assess AAV genome integrity beyond ITR-2 using an extended ddPCR method for precise quantification of empty and full capsids with various genomic targets.

• Performance Comparison Of The Vericheck ddPCR™ Empty-Full Capsid Kit And Analytical Ultracentrifugation (AUC)

  Discover how Droplet Digital PCR (ddPCR) offers a precise analysis of AAV capsid content, outperforming analytical ultracentrifugation (AUC) in distinguishing therapeutic genomes from contaminants.

• Designing A Disinfectant Study For Your Cleanroom

  Disinfectant efficacy studies are crucial for safeguarding the sterility of your manufacturing facilities. Gain expert insights into the intricacies of these important studies and how to design one.

• Aseptic Filling Solution Enhances Sterility Assurance for Pharma Manufacturer

  Emergent BioSolutions upgraded its Winnipeg site with the Cytiva SA25 aseptic filling workcell to improve sterility assurance, product flexibility, and regulatory compliance for CGT manufacturing.

• A Biosafety Cabinet For Virology Studies And Disease Surveillance

  Discover how Germfree tackled a unique challenge from the Public Health Agency of Canada by designing a custom Class III biosafety cabinet for advanced virology studies and disease surveillance.

• High-Yield Expression Of Complex Proteins From Stable Pools

  This study presents the development of apoptosis-resistant CHO cell lines (DKO1 and DKO2), using electroporation technology, with the goal of enhancing biotherapeutic production.

• Quality Control Of Oligonucleotides Using HPLC Coupled To UV And MS Detection

  Efficient quality control of therapeutic oligonucleotides is crucial. Explore advanced methods combining HPLC-UV and mass spectrometry for precise impurity quantification and mass confirmation.