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TRANSLATIONAL RESEARCH

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Elucidating The Role Of IL-18 In NSCLC Integrated Analysis

Hear how imaging mass cytometry, CyTOF, and single-cell sequencing unlock the secrets of the tumor microenvironment. Discover new insights into IL-18 and its impact on non-small cell lung cancer.

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Analytics & Assays: Defining mRNA Therapeutic Impurities Early & Often

mRNA therapeutics present a whole new safety paradigm not seen in vaccine applications. In this segment, Combined Therapeutics CSO Thomas Van Cott, Ph.D. and Omega Therapeutics Executive Director, Process Development and Analytical Sciences Jeff Atkinson, Ph.D. address th...

2:56 Milliporesigma
GLP And The Impact To Start Up Companies

Good Laboratory Practice is often used in laboratories and is necessary for specific investigations. What does it mean? And how can it help start-up companies? Watch this video to learn more.

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Saudi Arabia Government Leaders Discuss Agile Manufacturing Beyond Borders

Learn how government leaders in Saudi Arabia planned for biopharma resilience beyond borders and used agile manufacturing to prepare for the unknown.

1:48 LMSMS Analysis Of Coproporphyrin And Coproporphyrin III In Human Plasma
LC/MS/MS Analysis Of Coproporphyrin 1, Coproporphyrin 3 In Human Plasma

This innovative approach holds promise for reducing the need for extensive clinical drug-drug interaction studies, potentially streamlining the drug development process.

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Can Kinetics Provide Detailed Information About Binding Interactions?

See the potential value kinetics brings to deepen the understanding of biological processes.

1:49 Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup
Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup

By leveraging this innovative combination, the assay achieves detection limits comparable to traditional methodologies while enhancing overall efficiency and reliability.

4:13 Bio-Plex Technology and Solutions
Bio-Plex® Technology and Solutions

See how the Bio-Plex system allows researchers and clinicians to obtain precise results with less time and effort, using lower sample volumes in a high-throughput format.

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How To Best Optimize mRNA Production Workflows

Multiple steps in the mRNA manufacturing process can appear more complex than they have to be. Learn how to simplify your approach and produce the best possible mRNA vaccines and therapeutics.

1:37 Antisense
Antisense Oligonucleotide Extraction Optimization Reveals Differences

Our findings provide critical insights into refining ASO extraction protocols, which can enhance the accuracy of downstream analyses and support further research into ASO-based therapeutics.

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Can You Run Crude Samples Using An SPR Instrument?

We explore a common misconception and provide examples of complex material being used in an SPR system.

5:18 Meet The ZE5 Cell Analyzer from Bio-Rad
Meet The ZE5™ Cell Analyzer from Bio-Rad

Designed by users for users this video shows how customer feedback directly resulted in the creation of an instrument that addresses gaps in other flow cytometry instruments.

2:12 Droplet Digital PCR Systems
Droplet Digital PCR Systems

Droplet Digital PCR (ddPCR) simplifies the quantification of host cell DNA in process development, quality control, and biomanufacturing processes.

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Is The Sensitivity Of Optical Biosensors Important?

Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.

26:46 Droplet Digital PCR For Host Residual DNA Quantification
Droplet Digital PCR For Host Residual DNA Quantification

In this presentation principal scientist for Merck Research Laboratories Dr. Hussain, discusses an extraction-free method in which samples are subjected to digital PCR.

Addressing Some Of The Most Common Surface Plasmon Resonance Questions

This video series addresses some of the most common SPR questions around evaporation, kinetics, sensitivity, and more.

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Using ddPCR Technology To Characterize The Poly(A) Tail Content

When characterizing 3’ poly(A) tail length and integrity, Droplet Digital PCR technology demonstrates an orthogonal or alternative method to help ensure the quality and consistency of mRNA products.

1:47 LC MS  Method For The Measurement Of Ornithine Carbamoyl Transferase Enzymatic
LC/MS Method For Measurement In Human Plasma

According to the researchers, this plasma-based measurement has the potential to serve as a critical pharmacodynamic biomarker, facilitating the assessment of novel therapeutic approaches.

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Is Evaporation Important For Optical Biosensors?

If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?

3:43 Aliri - Shane Karnik
A Derivatization-Free LCMS Assay For 4β-hydroxycholesterol

Learn about a novel LCMS assay for 4β-hydroxycholesterol, a key biomarker for CYP3A activity. This derivatization-free method offers a faster and more efficient approach for clinical studies.