TRANSLATIONAL RESEARCH
Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup
By leveraging this innovative combination, the assay achieves detection limits comparable to traditional methodologies while enhancing overall efficiency and reliability.
How To Best Optimize mRNA Production Workflows
Multiple steps in the mRNA manufacturing process can appear more complex than they have to be. Learn how to simplify your approach and produce the best possible mRNA vaccines and therapeutics.
Using ddPCR Technology To Characterize The Poly(A) Tail Content
When characterizing 3’ poly(A) tail length and integrity, Droplet Digital PCR technology demonstrates an orthogonal or alternative method to help ensure the quality and consistency of mRNA products.
Streamline Your mRNA Purification Steps
Ensure your mRNA's stability and effectiveness post-transcription with advanced filtration and chromatography techniques to enhance purity and recovery, which delivers high-quality mRNA for superior therapeutics and vaccines.
Audience Q&A | Inside The Most Promising Non-Viral Approaches To Genetic Engineering
Expert panelists, Dr. Robert Hariri, Chairman, founder, and CEO of Celularity, and Paul Kopesky, Ph.D., VP of Cell Therapy Process Development at Beam Therapeutics, provided detailed responses to our audience questions on electroporation, CRISPR, delivery technologies bey...
Early-Phase Whole-Body PK
Accelerate your path to the clinic with Aliri’s cost-effective, label-free whole-body PK service — designed to deliver deeper insights, faster decisions, and better outcomes for your drug candidates.
LC/MS Method For Measurement In Human Plasma
According to the researchers, this plasma-based measurement has the potential to serve as a critical pharmacodynamic biomarker, facilitating the assessment of novel therapeutic approaches.
Can You Run Crude Samples Using An SPR Instrument?
We explore a common misconception and provide examples of complex material being used in an SPR system.
Electroporation As A Method For Genetic Modification
In this clip, Dr. Robert Hariri, Chairman, founder, and CEO of Celularity, and Paul Kopesky, Ph.D., VP of Cell Therapy Process Development at Beam Therapeutics explain why electroporation has a higher gene editing efficiency than that of the viral vector method.
High Efficiency Cell Engineering From Concept To Clinic
Discover how highly efficient and scalable methods for engineering cells are accelerating the development and delivery of next-generation cell-based treatments for patients.
Why iPSC Is Research Thriving
In this first segment of Cell & Gene Live, Unlocking the Potential of iPSC Therapies in Regenerative Medicine, Julie Allickson, Ph.D., Chief Technology Officer at Mayo Clinic's Center for Regenerative Biotherapeutics and Erin Kimbrel, Ph.D., Head of Cell & Gen...
GLP And The Impact To Start Up Companies
Good Laboratory Practice is often used in laboratories and is necessary for specific investigations. What does it mean? And how can it help start-up companies? Watch this video to learn more.
Achieving Stability For mRNA
Expert panelists for this Cell & Gene live event share some of things researchers are exploring to keep mRNA more stable.
Saudi Arabia Government Leaders Discuss Agile Manufacturing Beyond Borders
Learn how government leaders in Saudi Arabia planned for biopharma resilience beyond borders and used agile manufacturing to prepare for the unknown.
Plasmid Complexity And The Push For Stronger CGT Material Control
In this segment of Cell & Gene Live, Anthony Blaszczyk, Ph.D., Senior Scientist at the U.S. Pharmacopeia, and Basak Clements, Ph.D., Founder and Senior Advisor at biomatria, were joined by Cell & Gene Chief Editor Erin Harris to discuss why complex materials such ...
Is The Sensitivity Of Optical Biosensors Important?
Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.
Mitigate Clinical Risk In Cell Therapy Development With A GMP Compliant Process
Help shape the future of medicine by building better, safer cell therapies. See how expertise in scalable, GMP-compliant cell engineering can effectively mitigate clinical development risks.
Elucidating The Role Of IL-18 In NSCLC Integrated Analysis
Hear how imaging mass cytometry, CyTOF, and single-cell sequencing unlock the secrets of the tumor microenvironment. Discover new insights into IL-18 and its impact on non-small cell lung cancer.
Can Kinetics Provide Detailed Information About Binding Interactions?
See the potential value kinetics brings to deepen the understanding of biological processes.
Safety And Efficacy Advancements In Genome Editing
Paul Kopesky, Ph.D., VP of Cell Therapy Process Development at Beam Therapeutics shares his take on the high frequency of productive edits for base editing. In addition, Celularity’s Chairman, Founder, and CEO, Dr. Robert Hariri, shares how he sees non-viral gene de...
Real-Time Monitoring And Automated Sampling For Enhanced Efficiency
Integrating real-time, in-line monitoring with automated sampling in bioprocessing enhances efficiency and precision. Discover how advanced spectroscopy provides non-destructive insights to optimize cell growth and productivity.
Non-Viral Tools For Genome Engineering
In this segment, Dr. Robert Hariri, Chairman, founder, and CEO of Celularity, and Paul Kopesky, Ph.D., VP of Cell Therapy Process Development at Beam Therapeutics each share their own take on the tools, platforms, and non-viral approaches they have used for genome enginee...
Why Material Definitions Matter In Cell And Gene Therapy
In this first segment of Cell & Gene Live, Anthony Blaszczyk, Ph.D., Senior Scientist at the U.S. Pharmacopeia, and Basak Clements, Ph.D., Founder and Senior Advisor at biomatria, were joined by Cell & Gene Chief Editor Erin Harris to discuss why cell and gene the...
An All-In-One Solution For Residual DNA Quantitation
Explore an all-in-one solution for residual DNA quantitation with a 3D lab tour with virtual demos, videos, and interactive instrument guides to experience the full workflow.
NK Cells' Role In Non-Viral Approaches To Genetic Engineering
Here, Dr. Robert Hariri, Chairman, founder, and CEO of Celularity, and Paul Kopesky, Ph.D., VP of Cell Therapy Process Development at Beam Therapeutics each share their take on the primary challenge to modifying NK cells.
Ori Spotlight: Building Early-Phase CGT Infrastructure For Translational Success
Tighter integration between research, process development, and manufacturing is key to accelerating the translation of cell therapies from the lab to the clinic. Learn how a leading academic center is doing it.
Major Advancements In mRNA
Experts on this Cell & Gene live event discuss the major scientific biological advances in understanding the potential for mRNA-based immunotherapies vaccines for cancer over the last 2 years.
LC/MS/MS Analysis Of Coproporphyrin 1, Coproporphyrin 3 In Human Plasma
This innovative approach holds promise for reducing the need for extensive clinical drug-drug interaction studies, potentially streamlining the drug development process.
Antisense Oligonucleotide Extraction Optimization Reveals Differences
Our findings provide critical insights into refining ASO extraction protocols, which can enhance the accuracy of downstream analyses and support further research into ASO-based therapeutics.
Addressing Some Of The Most Common Surface Plasmon Resonance Questions
This video series addresses some of the most common SPR questions around evaporation, kinetics, sensitivity, and more.