TRANSLATIONAL RESEARCH
Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup
By leveraging this innovative combination, the assay achieves detection limits comparable to traditional methodologies while enhancing overall efficiency and reliability.
A Derivatization-Free LCMS Assay For 4β-hydroxycholesterol
Learn about a novel LCMS assay for 4β-hydroxycholesterol, a key biomarker for CYP3A activity. This derivatization-free method offers a faster and more efficient approach for clinical studies.
How To Best Optimize mRNA Production Workflows
Multiple steps in the mRNA manufacturing process can appear more complex than they have to be. Learn how to simplify your approach and produce the best possible mRNA vaccines and therapeutics.
Analytics & Assays: Defining mRNA Therapeutic Impurities Early & Often
mRNA therapeutics present a whole new safety paradigm not seen in vaccine applications. In this segment, Combined Therapeutics CSO Thomas Van Cott, Ph.D. and Omega Therapeutics Executive Director, Process Development and Analytical Sciences Jeff Atkinson, Ph.D. address th...
Addressing Some Of The Most Common Surface Plasmon Resonance Questions
This video series addresses some of the most common SPR questions around evaporation, kinetics, sensitivity, and more.
Saudi Arabia Government Leaders Discuss Agile Manufacturing Beyond Borders
Learn how government leaders in Saudi Arabia planned for biopharma resilience beyond borders and used agile manufacturing to prepare for the unknown.
Using ddPCR Technology To Characterize The Poly(A) Tail Content
When characterizing 3’ poly(A) tail length and integrity, Droplet Digital PCR technology demonstrates an orthogonal or alternative method to help ensure the quality and consistency of mRNA products.
Early-Phase Whole-Body PK
Accelerate your path to the clinic with Aliri’s cost-effective, label-free whole-body PK service — designed to deliver deeper insights, faster decisions, and better outcomes for your drug candidates.
Is The Sensitivity Of Optical Biosensors Important?
Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.
Ori Spotlight: Building Early-Phase CGT Infrastructure For Translational Success
Tighter integration between research, process development, and manufacturing is key to accelerating the translation of cell therapies from the lab to the clinic. Learn how a leading academic center is doing it.
Can You Run Crude Samples Using An SPR Instrument?
We explore a common misconception and provide examples of complex material being used in an SPR system.
Is Evaporation Important For Optical Biosensors?
If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?
Can Kinetics Provide Detailed Information About Binding Interactions?
See the potential value kinetics brings to deepen the understanding of biological processes.
Elucidating The Role Of IL-18 In NSCLC Integrated Analysis
Hear how imaging mass cytometry, CyTOF, and single-cell sequencing unlock the secrets of the tumor microenvironment. Discover new insights into IL-18 and its impact on non-small cell lung cancer.
GLP And The Impact To Start Up Companies
Good Laboratory Practice is often used in laboratories and is necessary for specific investigations. What does it mean? And how can it help start-up companies? Watch this video to learn more.
Antisense Oligonucleotide Extraction Optimization Reveals Differences
Our findings provide critical insights into refining ASO extraction protocols, which can enhance the accuracy of downstream analyses and support further research into ASO-based therapeutics.
LC/MS Method For Measurement In Human Plasma
According to the researchers, this plasma-based measurement has the potential to serve as a critical pharmacodynamic biomarker, facilitating the assessment of novel therapeutic approaches.
LC/MS/MS Analysis Of Coproporphyrin 1, Coproporphyrin 3 In Human Plasma
This innovative approach holds promise for reducing the need for extensive clinical drug-drug interaction studies, potentially streamlining the drug development process.