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CELL AND GENE THERAPY MANUFACTURING

3:46 Thermo Screen splash
Singapore Single-Use Site Capacity Expansion

Thermo Fisher Scientific is expanding our single-use manufacturing network globally, an expansion site closer to Asia Pacific region

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Scalable Production Of Lentivirus For Research To Commercial Manufacturing

Join our webinar on scaling the CTS LV-MAX System in bioreactors, covering transfection scalability, Thermo S.U.B. advantages, and DynaSpin’s efficient gene therapy integration.

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Focal Points for 2024: Dr. Verdun and Dr. Marks Talk Regulatory Challenges for Cell-Based Therapies

Dr. Verdun and Dr. Marks provide detailed feedback on the regulatory challenges facing cell therapy and explain the Agency’s most important focal points for 2024, patient accessibility, and more.

2:07 Thermo Fisher 1
How To Fill And Empty Nunc Standard Cell Factory System

Watch this step by step how to instructional video to learn how to fill and empty the Thermo Scientific Nunc Standard Cell Factory System, which is compatible with the same cell culture techniques used in smaller cell culture vessels.

0:37 captureselect affinity
CaptureSelect Affinity Chromatography

30-second video sharing a visualization of our CaptureSelect affinity chromatography capability. The target protein binds with VHH molecules immobilized on the chromatography beads, non-target proteins are removed, and the eluted fraction contains a high yield of pur...

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Autoimmune Disease Research's Impact On The Development Of Cell Therapies For Oncology

Recently, many cell therapy companies have been pivoting to autoimmune diseases. Expert panelists discuss whether they think there are any learnings or potential headwinds these pivots could provide to cell therapies for oncology.

4:24 Interview With Pharma Analytics Field Application Specialist - Sandi True
Interview With Pharma Analytics Field Application Specialist - Sandi True

Hear Sandi True, a Field Applications Specialist discuss helping customers navigate challenges often encountered when evaluating and implementing Residual DNA Quantitation, Mycoplasma Detection, and Microbial Identification Assays.

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Major Advancements In mRNA

Experts on this Cell & Gene live event discuss the major scientific biological advances in understanding the potential for mRNA-based immunotherapies vaccines for cancer over the last 2 years.

2:33 Ingress Leak Test For Bioprocess Containers
Ingress Leak Test For Bioprocess Containers

When a visual inspection with magnification isn't enough, the IPA ingress test can definitively confirm a leak. Learn how to perform this critical quality test.

18:56 Enhancing AAV Purification In Gene Therapy Manufacturing
Enhancing AAV Purification In Gene Therapy Manufacturing

Review chromatography solutions for purifying multiple AAV serotypes, with specialists’ insights on bioprocessing and downstream optimization.

3:10 Louis Sacco
Expanding Manufacturing Of Purification Resins To Align With Customer Demands

Discover how scaling up processes and building out facilities has allowed for end-to-end solutions that meet customer requirements for both supply and quality in their production lines.

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Supply Chain And Operational Challenges Facing mRNA

Explore some of the biggest supply chain challenges facing mRNA cancer therapeutics and what short-term solutions may exist, starting with Chain of Custody/Chain of Identity.

25:28 Multi-Omics And Bioinformatics In Cell Culture Media Design
Multi-Omics And Bioinformatics In Cell Culture Media Design

Learn about the impact of a multi-omics analysis, utilizing proteomics and metabolomics, in the development and optimization of media with the goal of improving titer, and making development and manufacturing more efficient.

5:02 Thermo Fisher Scientific Suzhou, China Manufacturing Site Capabilities
Thermo Fisher Scientific Suzhou, China Manufacturing Site Capabilities

Watch this video to learn more about this manufacturing site capabilities, quality management systems, PPI implementation, product expansion, assurance of supply and lead times.

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Safety And Efficiency Of Source Material Collection

Expert CTO's detail how automation improves safety and efficiency when collecting source material.

43:42 Simple In-House Mycoplasma Testing Method
Simple In-House Mycoplasma Testing Method For Regulatory Expectations And Rapid, Confident, And Actionable Results

In this webinar, we present an overview of worldwide regulatory guidance for mycoplasma testing, as well as a mycoplasma testing method that has been accepted by regulatory authorities worldwide across various therapeutic modalities.

24:18 Inside Bioprocessing Continuous Perfusion
Inside Bioprocessing: Continuous Perfusion

Learn about the essential elements of upstream workflows, media optimization strategies, and liquid handling logistics required to implement continuous perfusion successfully.

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Defining The CMC / Clinical Relationship For Allogeneic Cell Therapies

During this segment, Nguyen and Wagner define why the relationship between CMC and Clinical is so critical, and they also explain what a mutually beneficial partnership between CMC and Clinical looks like.

1:10 Nalgene Ultralow Particulate Bottles And Carboys
Ultralow Particulate Bottles And Carboys: Where Being Particular About Particulates Is Critical

Optimize your operations with ready-to-use, meticulously prepared containers. Learn how our commitment to cleanliness reduces risks and supports your most critical requirements.

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Unlocking The Future Of Allogeneic Cell Therapy For Oncology | Audience Q&A

Expert panelists in this Cell & Gene Therapy Live presentation provided detailed responses to questions about the potential risks of CAR-T therapy, screening criteria for donor material, comparability, and more.

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Understanding AI And Machine Learning's Impact On CGT with Dr. Peter Marks and Dr. Nicole Verdun

During this segment, Dr. Peter Marks and Dr. Nicole Verdun share their take on how AI and machine learning will impact FDA regulation in 2024.

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mRNA For Cancer Immunotherapy 2024 Outlook | Audience Q&A

During our Cell & Gene Live, mRNA For Cancer Immunotherapy 2024 Outlook, our expert panelists answered audience questions regarding patient safety, foreseeable challenges in mRNA cancer immunotherapy for solid tumors, and much more.

20:50 Scalable Purificaiton Of In Vitro Transcribed mRNA
Scalable Purification Of In Vitro Transcribed mRNA

Learn more about how affinity-based mRNA chromatography resin facilitates the purification and isolation of mRNA from in vitro transcription (IVT) manufacturing processes.

5:05 Perfusion Hardware Needs
Perfusion: Hardware Needs

In this video, we will discuss cell retention mechanisms, pumps, and intensification challenges in the perfusion process.

59:51 GettyImages-597971944-viral-vector-AAV-adeno-associated-virus
Upstream To Downstream: A Comprehensive Approach To AAV Production

How can you face the challenges of AAV production, scale up your AAV manufacturing effectively, and enhance the recovery and purity in your downstream processing.

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Why Clinical Requirements Change: Dr. Peter Marks on Pre-IND Meeting Pathways

Learn how clinical requirements change after the FDA and a company agree on a pathway during a pre-IND meeting and how the company might recover as a result.

4:03 Andy Davies
Enhanced Chromatography Resins For Faster, More Efficient Purification

Learn from an industry veteran about the evolution of protein purification, from early equipment to modern, agile solutions, emphasizing continuous improvement and customer-centric approaches.

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Quality Roundtable: Optimizing Biologics Manufacturing Processes With Raw Materials

Improve your commercial manufacturing process with advice from regulatory and raw materials experts on the development journey from pre-clinical to licensure.

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Innovative Contamination Control: Enabling Integrity And Efficiency

An integrated approach can enhance contamination control, boost process efficiency, and ensure the production of high-quality cell therapy products.

59:11 Manufacturing Considerations For Viral & Non-Viral Platform Selection
Manufacturing Considerations For Viral & Non-Viral Platform Selection

In this webinar, a panel of experts spanning the lentiviral vector, exosome and oncolytic virus fields will discuss the impact of manufacturing considerations on their respective platform selection and ongoing product/process development strategies.