Optimization Of Anion Exchange Purification For The Large-Scale Production Of Plasmid DNA

Plasmid DNA has several therapeutic applications, and its large-scale production can be achieved in a flexible and scalable way using an anion exchange purification step. Thermo Fisher Scientific has developed a variety of anion exchange resins well-suited for plasmid purification, designed to simplify workflows and increase yield and purity. These resins use the unique POROS bead technology to assist in overcoming many of the challenges of large-scale plasmid purification.