product datasheets, catalogs, app notes
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A Platform Standard For Viral Vector Manufacturing And Commercialization
4/6/2022
Learn more about platform technologies that are being developed and implemented to support large-scale production of viral vectors.
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EX-CELL® CD Insect Cell Medium
3/29/2022
A chemically defined medium specially formulated to get the best performances for insect cell lines. The formulation is animal-component free and has been formulated with L-Glutamine.
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Sf-RVN® Insect Cell Line
3/29/2022
The Sf-RVN® Insect Cell Line is a rhabdovirus-negative Sf9 cell line that can be grown in both adherent and suspension culture.
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AAV Process Development Guidance Based On Cost Modeling
3/16/2022
Cost modeling can be a powerful tool to assist with prioritizing areas of focus for process improvement during process development and especially useful for processes producing viral vectors for gene therapies.
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Multivariate Inter-Stage Batch Profile Monitoring And Future State Estimation For Efficient Manufacturing Operations
2/3/2022
How much quicker and easier would it be if we could know the process’s health by looking at a single metric rather than checking hundreds of parameters?
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MilliporeSigma Gene Therapy Capabilities
9/22/2021
You’ve created a gene therapy with the possibility to help patients. But the development and manufacturing of your gene therapy, how it’s developed, produced and approved, are still being outlined. No process template exists. Our products and services for AAV, Lentivirus and other viral vectors provide solutions to your most challenging pain points around process development, speed, manufacturing and regulatory guidelines.
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Stemline® Platform Media – For Optimized Stem Cell Expansion
9/7/2021
To obtain enough cells for stem cell-based therapies, ex vivo expansion is utilized to ensure successful engraftment and economize the manufacture of both allogeneic and autologous therapies. We have developed the Stemline® Platform of cGMP-manufactured media, optimized for the expansion of various adult stem cell types in automated manufacturing environments.
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CellPrime® rAlbumin
8/25/2021
CellPrime® rAlbumin is a non-animal origin (NAO) recombinant media supplement that is GMP manufactured according to EXCiPACT™. It combines excellent quality with superior performance and lot-to-lot consistency.
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Optimization Strategy And Process Economics Of DNA Digestion In Viral Vector Production For Gene Therapy
12/16/2020
Benzonase® endonuclease is a high-quality product delivering immense value to viral vector processes. The enzyme activity is strongly influenced by the matrix, and optimization of its use should be a mandatory step in process development. In this application note, we highlight an optimization strategy and process economics of DNA digestion in viral vector purification.
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Tangential Flow Filtration (UF/DF) Of Plasmid DNA
12/16/2020
Learn how optimization of hydraulic parameters can help you achieve the desired plasmid purity, formulation, and concentration specifications.