product datasheets, catalogs, app notes
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AAV Process Intensification Using High Salt Lysis And Salt Tolerant Endonuclease
3/25/2024
In the production of adeno-associated virus (AAV) vectors, cell lysis involves challenges addressed through high salt concentrations and a salt-tolerant endonuclease, enhancing titer and infectivity.
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Novel Enzyme For Nucleic Acid Removal At High Salt Concentrations
3/25/2024
Learn about a best-in-class solution designed for efficient nucleic acid removal at high salt concentrations.
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Automated Aseptic Sampling For Upstream Bioprocessing
1/2/2024
Explore PAT, the use of automated sampling technology to accelerate analytical and quality control methods, the benefits of automated sampling in upstream process development, and more.
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A 2 mL Automated Perfusion Cell Culture Platform
12/5/2023
The Mobius® Breez Microbioreactor is designed to support gentle, adaptable, and reproducible cell processes. Learn how it enables you to increase efficiency and reduce development timelines and costs.
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Testing Cell-Based Immunotherapeutics For Microbial Contaminants
10/23/2023
In this study, two different immune cell preparations were evaluated for their compatibility with the Milliflex® Rapid System to establish a USP and EP compliant method for rapid sterility testing.
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Optimizing And Scaling Lentiviral Vector Production
10/23/2023
Here, we outline how the upstream and downstream workflows of the VirusExpress® platform for lentiviral vectors were optimized through the use of design of experiments and supplementary studies.
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Accelerating Bulk Harvest Testing Using A CHO Animal Origin Free Virus Panel
10/19/2023
Here, we describe the design and performance of a degenerate PCR-based approach to broad virus screening that can be used in testing bulk harvest material derived from CHO cells.
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Innovative Single-Use Tangential Flow Filtration (TFF) Devices
9/26/2023
Pellicon® Capsules with Ultracel® membrane are innovative single-use tangential flow filtration (TFF) devices for streamlined bioprocessing, ideal for the filtration of solutions that require single-use capabilities.
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Development Of A Novel Cell Culture Medium For AAV Production
9/26/2023
Explore the medium development process of a novel cell culture medium for AAV production with multiple HEK293 lineages, which was performed with three different HEK293 cell lines to maximize AAV titers.
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Scalability And Performance Of Single-Use Bioreactors
8/1/2023
Here, we provide scalability data as a guide for process development and cross-scale performance expectations and characterize performance attributes of the impeller, spargers, Ultimus® film, and sensors.