Milliporesigma Brochures

  1. Gene Therapy Capabilities For AAV And Lentivirus Production

    Explore all of our gene therapy solutions for AAV and Lentivirus manufacturing based on 30+ years of experience to help bring your therapy to life. 

  2. Analytical Development And Characterization For AAV

    Our assay packages and phase-appropriate assay development and validation capabilities provide the product and process knowledge you need to develop a QTPP and identify the CQAs for your therapy.

  3. AAV Biosafety Testing & Characterization Services

    Biosafety testing and characterization for new products are essential as they emerge for clinical study. Both measures will help mitigate safety concerns and confirm product quality before these therapies are administered to patients. Our BioReliance® AAV testing services give you the confidence to get your products to market quickly and safely.

  4. Single-Use Fluid Management

    Mobius® 2D and 3D assemblies, filtration, storage, and transportation solutions are key components for efficient, ergonomic, and scalable single-use fluid management. This interactive brochure is designed to provide you with an overview of our complete single-use fluid management offerings, and a detailed guide to a holistic risk mitigation approach to quality control and assurance to meet your regulatory and compliance needs.

  5. Analytical Development And Characterization For mRNA

    Meet your mRNA product's specific needs with assay packages that provide the product and process knowledge needed to develop a quality target product profile and identify critical quality attributes.

  6. Viral Clearance Services

    Ensure safety with expert-led viral clearance studies. Our global team delivers regulatory-compliant, scientifically robust solutions to eliminate viral risks and support your product’s success.

  7. A Transfection-Based Solution With Proven Performance At Scale

    The VirusExpress® 293 AAV Production Platform offers a transfection-based solution using a suspension-adapted cell line, which is GMP banked and characterized chemically defined medium, and a process with proven performance at a clinically relevant scale.

  8. VirusExpress 293 AAV Production Platform

    The VirusExpress® Platform offers a transfection-based solution to Adeno-Associated Viral (AAV) production challenges, featuring a suspension adapted cell line, chemically defined medium, and a clinically relevant process dramatically reducing time to commercial production.

  9. Single-Use Sterile Sampling Assemblies

    Improve your single-use manufacturing processes with standard, closed, and sterile sampling assemblies.

  10. Optimization Of Benzonase® Endonuclease Use In Virus Purification

    The use of Benzonase® endonuclease additionally increases the yield in virus purification, protects the downstream chromatography and filter devices from fouling and reduces feed stream viscosity. In this document we will provide you guidance on how to plan and set up a Design of Experiments (DoE) optimization experiment of Benzonase® endonuclease in your viral gene therapy process.