MilliporeSigma Articles

  1. Benefit From Leveraging Perfusion Early In Process Development 4/5/2024

    By addressing the complex needs of cell culture from the start, organizations can take steps to optimize their process, ensuring they are maximizing productivity and product quality.

  2. Advancing A LNP Formulation To Clinical And Commercial Manufacturing 3/25/2024

    Lipid selection impacts the final LNP drug product and the LNP process. Review critical quality considerations for lipids and the process requirements for successful commercial-scale manufacturing.

  3. Strategies For The Separation And Analysis Of Empty And Filled Capsids 1/23/2024

    Explore approaches for the capture and separation of capsids, upstream strategies for reducing the level of empty and partially filled capsids, trends in AAV capsid design impacting purification, and more.

  4. Perspectives On The Adoption Of Fully Closed Processing 1/16/2024

    In this study, industry experts share their perspectives and plans related to the implementation of fully closed processing. Explore the drivers and challenges of fully closed processing and more.

  5. Streamlining And Enhancing Gene Therapy Production With Automation 1/9/2024

    When it comes to determining the appropriate analytics to inform early development, there are a number of variables to consider surrounding cost, operator expertise, and throughput.

  6. What To Consider For A Modular Facility With Closed Processing 1/2/2024

    The emerging trends in the biopharmaceutical industry are driving an even greater need for modular facilities and closed processing. Learn about the progression toward closed processing and more.

  7. The Post-Pandemic Supply Chain: Improving Resilience Via Value Chains 11/14/2023

    The COVID-19 pandemic underscored the vulnerability of global supply chains. Explore lessons learned from the pandemic, the concept of supply chain resilience, what to look for in a supplier, and more.

  8. Streamlining Biomanufacturing Automation With Connectivity And Integration 10/29/2023

    Gain insight into the recent advancements in connectivity and integration technology, the associated challenges, and the importance of a vendor-neutral approach.

  9. Ensuring Biomanufacturing Resilience For Biologics And Vaccines 10/19/2023

    We highlight strategies for ensuring the reliable delivery of health technologies with a focus on vaccines, mAbs, and new modalities manufactured by biotechnology companies and institutes.

  10. Eliminating USP <88> In Vivo Animal Bioreactivity Testing For Polymer Characterization 8/25/2023

    There has been growing awareness about the environmental and ethical implications of plastics used in bioprocessing. The time for a shift to well-studied, proven in vitro cytotoxicity testing is now.