Featured Articles

  1. Analytics And Bioassays Can Safely Fast-Track mRNA-LNP Drug Development 2/23/2023

    One main mRNA technology challenge is the formulation of delivery systems like lipid nanoparticles (LNPs). Learn about evading impurities in lipids, the future of mRNA-based genomic medicines, and more.

  2. mRNA Product Purification Process Strategies 2/15/2023

    Impurities from IVT can induce undesired immune responses and negatively impact translation efficiency. Explore the pros and cons of each option for mRNA purification.

  3. mRNA Product IVT Process Insights 2/15/2023

    In vitro transcription (IVT) allows a researcher to tailor synthesis and introduce modifications to produce a transcript. Learn about IVT along with process challenges and strategies.

  4. mRNA: Challenges And Strategies Related To The DNA Template Process 2/15/2023

    Encapsulated mRNA–LNP creation begins with synthesizing the DNA template. Explore insights on DNA template synthesis, the challenges and strategies of generating a DNA template using PCR, and more.

  5. Boost LNP Drug Potency With Optimized Delivery Formulations 11/21/2022

    Lipid nanoparticles (LNPs) function as a drug delivery system for nucleic acids. Learn about the biomedical applications of LNPs as well as the anatomy, formulation optimization, and safety of LNPs.

  6. Drug Discovery And Screening, A Digital Era For RNA-LNP Therapeutics 11/21/2022

    Learn about the key stages of drug discovery and screening as well as how to overcome bottlenecks in screening mRNA-LNPs to rapidly develop genomic medicines.

  7. Navigating The Road To Reality For Allogeneic Cell Therapies 11/9/2022

    Allogeneic cell therapies offer great clinical promise, but they also pose unique challenges. Here, we highlight tips to make the translational journey easier.

  8. Bringing Allogeneic Cell Therapy To Patient Care 11/1/2022

    Bringing allogeneic cell therapy to patient care will require flexible, closed, and automated solutions to support the treatment options and increasing scale of the industry.

  9. Strategies To Overcome Delays In The Development Of Genomic Medicines 10/13/2022

    Learn how optimizing LNPs can help overcome drug-delivery challenges, unlocking potential new genomic medicines in a shorter time.

  10. Optimizing Capture And Polishing Steps In An rAAV Purification Process 10/13/2022

    We adapted an affinity capture step for rAAV2 and rAAV5, followed by a polishing step with rAAV5 to improve the yield of rAAV full capsids.