Featured Articles

  1. Scaling Up An Upstream Process For Gene Therapies 2/27/2025

    It's important to evaluate your starting point when scaling an upstream process. Review key considerations for deciding between adherent and suspension cells to optimize your gene therapy process.

  2. mRNA Vaccines And Therapeutics: Current Trends And Perspectives 2/25/2025

    Delve into the advancements and transformative impact of mRNA vaccine technology on modern medicine and explore how this technology is revolutionizing healthcare for the future and beyond.

  3. Tackling Encapsidated Host Cell DNA To Improve Quality 2/19/2025

    Discover a cell line that enhances rAAV production by reducing host cell DNA encapsidation, improving safety and efficiency through genetic modifications that inhibit apoptotic DNA fragmentation.

  4. Automation And Digital Solutions Can Help You Reach Your mRNA Manufacturing And Sustainability Goals 1/14/2025

    Explore how digital solutions help streamline mRNA manufacturing by reducing costs, improving efficiency, and supporting sustainability by creating paperless processes for emerging therapeutics.

  5. Toward A Gene Therapy Platform: What's The Best Format Of TFF? 1/13/2025

    Evaluate tangential flow filtration (TFF) formats and membrane chemistries for AAV gene therapy processing, assessing performance, scalability, economy, and closed processing options.

  6. Solvent-Free Purification Of D84-mer Oligonucleotide Using Capto™ PlasmidSelect Resin 1/13/2025

    Discover a solvent-free process using Capto PlasmidSelect and Capto Q ImpRes resins. They enable high-purity, scalable purification of long oligonucleotides, achieving more than 95% of full-length product purity.

  7. Single-Step Purification Of A 21-mer Oligonucleotide Using Capto™ Q ImpRes Resin 1/13/2025

    Explore how the oligonucleotide therapeutics market is advancing with scalable solutions for high-purity purification, supporting global production of life-changing RNA therapies.

  8. The Crucial Role Of Downstream Processing In Optimizing RNA-LNP Drug Development 8/28/2024

    Explore the key aspects of lipid nanoparticle (LNP) development, including the essential downstream processes of Tangential Flow Filtration (TFF) and normal flow filtration.

  9. Digital Solutions Advance Your mRNA Manufacturing Workflow 6/17/2024

    Explore the advantages of paperless manufacturing, the importance of incorporating a digital strategy early in the process, and how digital solutions for mRNA manufacturing can help enhance production.

  10. End-To-End Manufacturing Of Autologous CAR T Cell Therapies 6/13/2024

    Learn about a modular, functionally closed, end-to-end solution for the manufacture of autologous CAR T cell therapies.