FEATURED ARTICLES

• How To Design And Evaluate Bispecific Antibodies (BsAbs)?

  Bispecific antibodies combine two antigen-binding sites to enhance efficacy and safety. Their design requires structural strategy, MOA-based evaluation, and rigorous screening for optimal therapeutic performance.

• Analytical Approach For Bispecific Antibody Quality Study

  Bispecific antibody quality control demands advanced analytics to detect mispaired species, assess structural integrity, and confirm potency, ensuring safety and efficacy across diverse therapeutic applications.

• Efficient Late-Stage Development Of Biologics

  Reducing biologics manufacturing costs requires strategic late-stage process development, yield optimization, scale-up, and raw material substitution—all while maintaining product quality and regulatory compliance.

• Advances In High-Concentration Protein Formulation Development

  High-concentration protein formulations improve patient convenience but face challenges like viscosity, aggregation, and surfactant degradation. Innovative strategies optimize stability, scalability, and quality for advanced biologics development.

• Empowering Antibody Discovery With ProSpeed™

  Integrating linear expression technology into single B cell workflows accelerates antibody discovery, enabling early functional screening, improved sensitivity, and cost-effective identification of diverse therapeutic candidates.

• Challenges And Solution In The Poly (A) Control For Plasmid And mRNA

  Poly(A) tail integrity is critical for mRNA stability and translation. Advanced strategies optimize plasmid design, transcription, and purification to ensure consistent poly(A) control for therapeutic success.

• Early Discovery Of Functional Antibody Leads

  Early functional screening accelerates therapeutic antibody discovery, improving hit rates and efficiency through advanced platforms like hybridoma upgrades, single B cell workflows, and tailored phage display strategies.

• Quality By Design Meets Digital QMS In Advanced Therapies

  Risk-based quality systems, proactive problem-solving, and collaborative client relationships drive operational excellence, supported by digital QMS tools for compliance, deviation management, and continuous improvement in biomanufacturing.

• Comparing Gel, qPCR & HPLC For DNA/RNA Analysis

  Cost-effective agarose gel electrophoresis offers reliable plasmid supercoil and host DNA/RNA quantification, providing a practical alternative to qPCR and HPLC for biomanufacturing quality control.

• Efficient Plasmid Linearization: Type I & II Enzymes

  Advanced plasmid linearization improves transfection efficiency and gene expression, delivering high-purity DNA with rapid turnaround, low endotoxin, and scalable processes for cell and gene therapy applications.

• Boosting Plasmid Yield & Integrity With PowerS-ITR

  PowerS-ITR E. coli platform boosts plasmid DNA yield, preserves ITR integrity, and reduces variability, enabling scalable, cost-effective manufacturing for gene therapy and vaccine applications.

• Efficient Viral Vector Production Cell Line — PowerSTM-293/293T

  Suspension-adapted HEK 293 cell lines enable scalable, cost-efficient AAV and LVV production, ensuring regulatory compliance, high yields, and process stability for cell and gene therapy development.