ABOUT CYTIVA
With a rich heritage dating back hundreds of years, Cytiva brings a wealth of technical expertise and talent, a broad and deep portfolio, and exceptional service help researchers and biopharma advance therapeutics at every stage from discovery to delivery.
We supply the tools and support our customers need to work better, faster, and safer, leading to the delivery of transformative medicines to patients. Our combined portfolio includes well-recognized names such as Allegro™, Supor™, iCELLis™, and Kleenpak™, in addition to ÄKTA™, Amersham™, Biacore™, FlexFactory™, HyClone™, MabSelect™, Sefia™, Whatman™, and Xcellerex™. Visit cytiva.com to learn more.
VIDEOS AND WEBINARS
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Learn about an easy to assemble and simple to use solution for laboratory TFF applications, the assembly of the system, and how to perform a continuous diafiltration.
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See how Pall innovative and time-saving life science research products simplify and speed up your critical workflow steps and allow for faster data analysis and results.
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For reagents, security of supply is a regulatory requirement, a factor that’s critical to consistently monitoring host cell protein (HCP) during the production of a biologic.
APPLICATION NOTES
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A streamlined approach to HPLC sample preparation can cut plastic waste by up to 79%. Find out how reducing consumables simplifies workflows and supports more sustainable, efficient lab operations.
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Compare membrane materials and pore sizes to assess their impact on flow rate and microbial recovery. See how fast filtration and ≥90% organism recovery offer guidance for selecting reliable membranes.
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Examine two rapid, high‑throughput strategies for small‑scale protein separation, using either multimodal resins or ion exchange membranes to achieve efficient, low‑volume purification.
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Learn how thoughtful filter selection can protect LC systems, improve protein recovery, and support reliable chromatographic results with key performance data and solvent compatibility insights.
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ULC microgel purification is often slowed by linear polymer contamination and limitations of centrifugation. Explore how hollow fiber TFF improves filtration efficiency and supports scalable processing.
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Optimize your protein purification workflow with tangential flow filtration by comparing membrane performance and exploring how protein concentration impacts flux and MWCO selection in lab-scale systems.
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Discover a simple, easy, and versatile method for capsule and depth filtration of small volumes that moves research from cell harvest to purification as quickly and efficiently as possible.
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In this study we evaluate the performance of the Pall NAB Nanosep centrifugal device for the isolation of SARS-CoV-2 viral RNA from human saliva samples spiked with heat inactivated virus using reagents (RCOM1 and RCOM2) from two commercially available kits for extraction of viral RNA.
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The most problematic step in the purification of synthesized biomolecules is the clarification of the sample once the cells are lysed. The lysate often contains biomolecule concentrations millions of times higher than the molecule of interest. Here we present a lysate sample preparation procedure using the AcroPrep™ Advance filter plate for lysate clearance that effectively removes unwanted cellular debris from samples.
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This application note demonstrates systems that have proven quite useful for clarification of mammalian cell cultures such as CHO-cells, by combining the cell clearance and sterile filtration functionality in a single device.
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Many techniques in Life Science research rely on efficient sample preparation methods. Concentration and purification of samples are key steps in the workflow that can greatly affect the outcome of the experimental results. Pall has increased the range of AcroPrep 24-well filter plates offered to help streamline membrane selection and provide effective solutions for multiple sample preparation needs. This document reports the data generated by ultrafiltration of proteins of known size with AcroPrep 24-well filter plates.
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Membrane filtration is the preferred method for sterility testing. Viscous products, such as oils, creams and ointments can prove difficult to filter. As per USP <71> viscous oils may be diluted as necessary with a suitable sterile diluent such as isopropyl myristate shown not to have antimicrobial activity in the conditions of the test. Sterile isopropyl myristate (IPM), has been shown to have no anti-microbial activity in test conditions. This study investigates the effectiveness of IPM as a diluent by comparing filtration times with unfiltered oils.
FEATURED PRODUCTS
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Membrane devices for sterilizing liquid reagents, removing particulate contamination, and clarifying solutions.
CONTACT INFORMATION
Cytiva
100 Results Way
Marlborough, MA 08855-1327
UNITED STATES
Phone: 800-526-3593
FEATURED ARTICLES
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The membrane filter technique offers a cost‑effective way to detect microbial contamination. See how it enables rapid detection and allows precise species identification using selective media.
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Efficient DNA and RNA purification is essential as sequencing and expression studies scale. Discover a multi‑well format that enables reliable binding across plasmid, genomic, and total RNA workflows.
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Efficient cell line development demands reliable clone selection and early removal of candidates. Filtration and sample prep solutions can strengthen sterility, simplify workflows, and support decisions.
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Membrane compatibility plays a crucial role in reliable sample filtration. Knowing how different filter materials interact helps prevent common workflow issues and supports efficient filtration.
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Filtration strategies help maintain sample integrity by reducing particulates and controlling contaminants. Learn why choosing the right pore size supports consistent, reliable biological workflows.
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Ultrafiltration offers a precise way to concentrate and purify proteins while removing smaller molecules. Learn how technique choice and membrane selection influence recovery, purity, and consistency.
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Learn about tangential flow filtration (TFF), typical TFF system configurations, ultrafiltration fundamentals, applications, system selection considerations, and more.
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Learn more on the importance of sterile filtration and how sterile filters are validated by the manufacturer and review the process and value of selecting the best prefilter to improve final sterile filtration performance.
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Learn how ultrafiltration devices in various steps of the cloning workflow can provide a more streamlined process compared to traditional methods of subcloning PCR-generated fragments.
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This article covers the concepts of protein concentration and diafiltration, comparing different ways of performing diafiltration and their impact on process time, volume, product stability, and recovery.