Laboratory Filtration Products For Clone Selection, Optimization And Recombinant Protein Analysis

Critical to delivering high titers of quality recombinant protein quickly is the selection and growth condition optimization of the best clone candidates from the initial pool of screened clones identified as expressing the protein of interest. Clone selection and optimization requires repeated analysis to identify clonal cell lines and cell culture variables that stably produce the highest titer protein expression.

Filtration and separation products play an important role throughout the clone selection process, from preparing and maintaining culture media, to venting bioreactors and further downstream processing steps. Filtration devices may also be used to purify samples prior to conducting functional analysis applications.

Pall supply a wide range of laboratory scale filtration and separation devices including high-throughput filter plates, centrifugal devices, syringe filters and capsule filters. Many of these devices are available in scalable formats, reducing the risk of changes to materials during scale-up to commercial manufacturing.

Learn about the many filtration products that can be utilized throughout a typical clone selection and optimization workflow.