Newsletter | February 19, 2026

02.19.26 -- Why In Vivo Therapies Fail When We Treat Them Like Ex Vivo Ones

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Webinar: Translating Stem Cell Programs to GMP: A Collaborative Approach to Overcoming Manufacturing Complexity

Stem cells are reshaping cell and gene therapy, but GMP readiness introduces unique risk. Join Landmark Bio’s Meytal Haviv for a practical discussion on advancing iPSC and stem cell programs from PD to GMP. Learn how process design, variability control, scaling strategy, and cross-functional execution impact reproducibility, regulatory alignment, and successful clinical translation. Click here to learn more.

FOCUS ON MANUFACTURING

Why In Vivo Therapies Fail When We Treat Them Like Ex Vivo Ones

For the next-generation cell and gene therapies, we must rethink design and controls, and we must reframe the problem from modality to architecture.

High Purity And Recovery With Adjustable Selectivity In Downstream Purification

Achieve high-yield purification of complex biomolecules. This resin supports fast flow rates and scalable performance to ensure consistent recovery across your downstream bioprocessing workflows.

Transforming T Cell Manufacturing Via Elutriation

Learn how this platform reduces manufacturing variability. By elutriating lymphocytes from apheresis, you can provide a more consistent cell product for your downstream manufacturing stages.

How To Choose The Right Isolator For Cell Therapy

Closed isolators provide the Grade A aseptic environments required for cGMP scaling. Explore how integrated automation and equipment ensure rigorous quality control for cell therapy production.

The Ultimate Guide To Stress-Free Pipetting

Improve accuracy and reduce stress with expert pipetting tips. Discover how technique and tool selection can boost precision and efficiency, ensuring consistent results across every lab workflow.

Considerations These Strategies For Buffer Preparation As You Grow

Buffer preparation strategies impact cost, efficiency, and risk. Compare in-house vs. outsourced approaches to help your teams align supply decisions with growth, operational needs, and long-term production goals.

Simpler, Faster, Cheaper Advanced Therapy Manufacturing

TFDF-based perfusion technology can boost lentiviral vector production by 10-fold. See how this approach slashes costs and accelerates the commercialization of CAR-T and other advanced therapies.

Evaluate Leachables Risk From Polymeric Single-Use Systems

Review best practices for evaluating risks from polymeric single-use systems. Gain the tools and insights needed to support robust assessments and maintain compliance in biomanufacturing stages.

Flexible Cell Culture Media For High Titer Production

Maximizing viral titers and full capsids requires systematic process development. Learn why choosing the right cell culture medium is foundational for optimizing AAV production in HEK 293 cells.

Advancements In Genome Integrity Assessment For Gene Therapies

Gene therapy holds promise for treating various genetic diseases. Delve into the latest in gene therapy with expert insights on AAV vector integrity, dPCR-based solutions, assay design, and reference standards.

How Can I Increase My Viral Titers And Improve The Percentage Of Full AAVs?

Explore various strategies to enhance viral titer and increase the percentage of full AAV capsids, like modifications to transfection reagents, cell lines, media, procedures, and more.

Overcome Scalability Hurdles In AAV Manufacturing

Address your concerns with traditional viral vector production processes by using a scalable upstream AAV production platform solution for viral gene therapies.

MANUFACTURING SOLUTIONS

Resin Resource Guide: Trusted For Biotherapeutic Purification - Bio-Rad Laboratories, Inc.

Digital Production Records For Modern Manufacturing - MasterControl, Inc.

Proteins For Optimizing Cell Proliferation And Function - FUJIFILM Biosciences

Testing Services To Navigate Clinical Challenges - MilliporeSigma

Safety And Pharmacovigilance In-House Services - Avance Clinical

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