Newsletter | July 29, 2025

07.29.25 -- Rethinking Large Animal Models In Gene Therapy With Novartis' Ralf Schmid, Ph.D.

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Analysis of Partial Capsids Using Vericheck ddPCR™ Empty-Full Capsid Kit

Accurate quantification of empty and full adeno-associated virus (AAV) capsids is critical for optimizing vectors in gene therapy. Explore the Vericheck ddPCR™ Empty-Full Capsids Kit from Bio-Rad, which is designed to offer a robust and reliable method for assessing capsid integrity, helping to ensure the consistency and effectiveness of AAV-based therapies.

FOCUS ON MANUFACTURING

Rethinking Large Animal Models In Gene Therapy With Novartis' Ralf Schmid, Ph.D.

On this episode of Cell & Gene: The Podcast, Host Erin Harris talks to Ralf Schmid, Ph.D., Associate Director of Preclinical Research at Novartis Biomedical Research, about the evolving use of large animal models in gene therapy development.

Scaling PSC Expansion From Bench To Pilot To Commercial Scale

Achieve reproducible and robust PSC expansion with proven best practices. This session covers single-cell passaging, perfusion feeding, and in-vessel harvesting.

Non-Viral Delivery Of Complex Cargos For Large-Scale T Cell Manufacturing

Explore an improved cartridge for the electroporation of complex cargos into large volumes of T cells. Discover how to achieve reliable, robust, and efficient delivery of complex, clinically relevant cargos.

The Paradigm Shift: From Scale-Up To Scale-Out In Genetic Medicine

The shift from "scale-up" to "scale-out" in genetic medicine enhances production speed, revolutionizing pharmaceutical manufacturing and accelerating life-saving therapies for global patient populations.

BSL-3 Mobile Biocontainment Laboratory For Vaccine Development Research

The client required a freestanding COVID-19 research facility on an accelerated timeline built for continuous use in the cold climate of the northeast United States without a shell building.

Cell Therapy Milestones, Challenges, And Forming The Future Of TILs

What enabled the evolution of TIL therapies? What does the future hold for them? And where should you concentrate your efforts to accelerate progress? Watch for answers to these questions and more.

Advancements In Aseptic Connection Technologies

Expand your knowledge on the latest innovation in the sterile connector space including the new 1.5” flow path connector, disconnection solution, and more.

Importance Of Data Reproducibility For Developing Safe Gene Therapies

What are viral-based vectors and why are reproducible quantitation of gene expression important in gene therapy? Explore these questions as well as the interplay among gene therapy vector components.

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Webinar: Hype vs Hands On: The Truth About End-to-End Manufacturing Automation

Invetech dives into the real-world tools reshaping cell and gene therapy manufacturing. Forget the lab—today’s bottlenecks are infrastructure. Discover how end-to-end automation, modular platforms, and AI-driven analytics can slash timelines, cut variability, and hardwire compliance. Learn how to spot automation opportunities early and future-proof your process for fast-changing therapies and regulatory demands. Don’t scale the science—industrialize it. Click here to learn more.

MANUFACTURING SOLUTIONS

Scale AAV Production Utilizing The Only Transfection Complex Stabilizer - Mirus Bio

Empower Your Bioprocess Journey With Innovative Solutions - Eppendorf SE

CellCube® System Protocol - Corning Life Sciences

A Cytokine Aids In Innate And Adaptive Immune Responses - Sartorius

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Webinar: Accelerating Cell & Gene Therapy Scale-Up With An Advanced Manufacturing Platform

Discover how Oribiotech and ElevateBio are revolutionizing cell and gene therapy manufacturing with IRO —a next-gen platform delivering superior biological performance, real-time monitoring, and automated scalability. This webinar reveals how closed, efficient systems reduce costs and complexity while boosting consistency and quality from early development to commercialization. Learn how to scale smarter and faster in the evolving CGT landscape. Register here.

EVENTS

Advancing the Future of Cell & Gene Therapy

This 11-12 November, Cell 2025 unites 1,000+ leading experts across the CGT value chain to solve key challenges, from scalable bioprocessing and regulatory hurdles to accelerating development timelines.

 

Gain practical strategies across cell culture, therapy development, and CGT manufacturing, and hear from world-renowned leaders Bobby Gaspar (CEO, Orchard Therapeutics), Christof Von Kalle, (Director & BIH Chair, Research Clinic Luxemburg), and Dame Molly Stevens (University of Oxford). Register Now

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