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| Showcasing a Scalable Downstream Platform for Multiple AAV Serotypes | Scientists need a downstream processing platform that can purify a variety of AAV serotypes with consistent recovery and quality to reduce timelines and complexity. In collaboration with iBET, we’ll show how you can select the right solutions to support scalable and high-performing AAV purification. Join us live on October 10th at 11:00 AM EST. Register here. |
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By BioPhorum | This article discusses how cell and gene therapy companies can use prior knowledge and platforms to leverage process characterization to reduce the testing and/or studies required during process validation for drug substance and drug product manufacturing processes. |
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| Using Robotics In The ATMP Space | Article | By Josh Russell, AST | With regulatory requirements and GMP recommendations trending towards less human interaction and more robotic automation, robotics is the way of the future for the ATMP industry. |
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| Accelerating Gene Edited Cell Lines With CRISPR Technology | Application Note | By Prathyushakrishna Macha, Ph.D., Danaher Life Sciences | This study establishes an effective and rapid process for developing a p53 knockout HEK-293 cell pool using CRISPR-based gene editing and antibiotic screening. |
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| Scaling Up The Learning Curve For Large-Scale AAV Manufacturing | Article | By David Bohonak and Ratish Krishnan, MilliporeSigma | The complexity of manufacturing AAV products, coupled with the challenges linked to controlling their costs, underscore the importance of improving the efficiency and scalability of these processes. |
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| Forget Lean Cleanroom Construction, Practice Lean Installation | Article | By Chad Smith, AES Clean Technology, Inc. | Lean construction, as a buzzword, gets a lot of play in the cleanroom industry for good reason. It is an idea that got its start with Toyota in the 1950s to maximize efficiency and eliminate waste in production. |
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| It's no secret that on-going research aims to improve the efficacy and specificity of non-viral approaches for genetic engineering. But the field is rapidly evolving with research aimed at improving transfection efficiency, targeting, and safety profiles of non-viral delivery systems. Join Cell & Gene Live to discuss the most notable approaches and recent breakthroughs as well as promising non-viral vectors used in clinical trials. Attendance is free thanks to the support of MaxCyte. |
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| Webinar: Innovative Contamination Control in Cell Therapy - Enabling Integrity and Efficiency | Join Thermo Fisher Scientific October 15th as we discuss how automated closed systems and larger bioprocess containers contribute to maintaining the integrity of cell therapy products and explain how rapid analytical assays can offer reliable and accurate contamination detection. Discover how an integrated approach combining these solutions can enhance contamination control, boost process efficiency, and enable the production of high-quality cell therapy products. |
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