Newsletter | April 1, 2024

04.01.24 -- Improving AAV Purity Upstream With PCL Manufacturing


Stem cells are the backbone of many allogeneic therapies and where they come from affects development and supply chain logistics, particularly cryopreservation. What temperatures are ideal to maintain product potency? How do you build a reliable cold chain? How do you work with existing infrastructure to allow for an “off-the-shelf” therapy? Don’t miss the next Cell & Gene Live digital event! Registration is free thanks to the support of Charter Medical and Bio-Techne.


Improving AAV Purity Upstream With PCL Manufacturing

The downstream separation of AAV capsids affects end-product purity and has been identified as a key pain point of the industry. Ultragenyx’s Dennis Huang advises starting with higher-quality yields upstream.


A Proven AAV Platform To Drive Down Program Costs And Maximize Speed

To ensure that your adeno-associated virus (AAV) therapy reaches patients as soon as possible, begin your relationship with an experienced AAV manufacturer early in the development journey.

3 Factors In Successful Orphan Drug Development And Manufacturing

Orphan drugs are extremely complex and hard to create. To help address this market barrier, learn more about controlling the process, identifying a global supply chain, and being flexible to scale with projects.

mRNA/saRNA Manufacturing: Streamlining RNA Production Processes

A look at key considerations for the production of RNA and strategies for successful scaling for commercial manufacture, specifically messenger RNA and self-amplifying RNA processes.

Set Your Oversight Early, But Do Not Dictate All The Rules

As more and more sponsors partner with CDMOs to leverage their expertise and capabilities, utilizing the right framework to manage a partner is crucial for the relationship to function optimally.

Lentiviral Vector Platform: Right The First Time

Leverage the right LVV manufacturing platform to accelerate timelines, better manage costs, and transform product development and potential for success so therapies can reach patients in need.


The BioCentriq Approach: Optimizing Products For Clinical Manufacturing

Infectious Diseases And Vaccines CRO Services

Technologies That Smartly Scale iPSC To Benefit Human Health

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