Article | August 15, 2023

Lentiviral Vector Platform: Right The First Time

Source: ElevateBio

By Mercedes Segura, Vice President, Process Development; Dawn Maier, Vice President, Emerging Technologies; and Bojiao Yin, Director of Vector Process Development, ElevateBio

Scientist Using Pipette GettyImages-1140779660

Lentivirus is a commonly used viral vector for delivering genes to cells, both directly in vivo and ex vivo, for engineering cells prior to infusion back into patients. Over the past twenty years, lentiviral vectors (LVVs) have been extensively optimized to improve their functional and safety features.

Explores the features and benefits of a LVV manufacturing platform designed to take solution-based approaches for producing LVV at volumes and purities that support any stage of product development. Leveraging the right platform can help accelerate development timelines, better manage costs, and transform product development and potential for clinical success so that life-changing medicines reach the patients that need them.

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