Newsletter | May 22, 2025

05.22.25 -- Hard Lessons In Parenteral Automatic Visual Inspection

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Webinar: Advanced Contamination Control for Cell Therapy: Automation, Assays, and Process Efficiency

This webinar explores contamination control in cell therapy manufacturing, focusing on automated closed systems, larger bioprocess containers, and rapid analytical assays. It highlights how these tools enhance sterility, efficiency, and product quality. Experts Alexandra Lisi and Sandi True will share insights into integrating these solutions for improved operational effectiveness. Click here to learn more.

FOCUS ON MANUFACTURING

Hard Lessons In Parenteral Automatic Visual Inspection

Complex problems can have simple solutions. That's what a team at AstraZeneca found when they set out to reduce false rejection rates in vials containing mAbs.

Reinventing Viral Vector Manufacturing For Decentralized Gene Therapies

Discover how scalable innovation is transforming viral vector production and driving broader, more equitable access to advanced gene therapies.

Optimize Your RNA-LNP Delivery With Ionizable Lipids

Discover how LNPs revolutionize intracellular drug delivery to enhance RNA vaccines, cell therapies, protein replacement, and gene editing.

AgentV's Virtues At The Vanguard Of Extracellular Vesicles

Learn about a novel solution dramatically improving the purification and yield of promising nanoscale vesicles for medical applications.

Simpler, Faster, Cheaper Advanced Therapy Manufacturing

Discover how TFDF-based perfusion technology boosts lentiviral vector production by over 10-fold, slashes costs, and accelerates the commercialization of CAR-T and other advanced cell therapies.

A Deep Dive Into QuickStart Media

Learn how this game-changing platform simplifies the complex process of custom media design, empowering researchers to expedite their development and achieve optimal results.

Evaluation Of Lentiviral Vector Stability And Development

Discover key findings that highlight the importance of evaluating LVV stability to develop a robust purification process. 

Comparing Activation Methods To Yield Clinical-Scale Expansion Of Gamma Delta T Cells

Data from the use of two distinct methods to generate billions of gamma delta T cells from peripheral blood mononuclear cells (PBMCs) is compared.

Lentiviral Vector Production Using Single-Use Bioreactors

Here, we outline a scalable and robust upstream process developed for LVV production of HEK293T cells and demonstrate how to expand HEK293T suspension cells.

Increasing iPSC Numbers Through Systematic Culture Process Optimization

Explore the use of a mini bioreactor system for stem cell culturing that optimized process parameters of a human induced pluripotent stem cell (hiPSC) culture in a step-by-step process.

Resolving Common Single-Use Concerns

Demand for single-use production tools, components, expertise, and capabilities continues to grow as innovative cell therapies evolve. However, concerns and misconceptions surround single-use solutions.

MANUFACTURING SOLUTIONS

VirusGEN Transfection Complex Stabilizer - Mirus Bio

Minimate EVO Tangential Flow Filtration System - Cytiva

Aliquotation Of Small Volumes At Highest Accuracy - Single Use Support

GMP Formulate And Fill System For Cell And Gene Therapy - Invetech

Transforming CGT With A Synergistic Partnership - Cencora

Accelerating Gene Therapy With The HIT SCAN Platform - Battelle

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