Cell And Gene Therapy Manufacturing

  1. Manufacturing Hurdles With Viral Vectors 11/13/2023

    With a wide range of viral vector-based drugs already approved, viral vectors are expected to remain the primary delivery mechanism for the foreseeable future. However, as the demand for viral vectors increases, addressing the challenges related to their manufacture and scale-up is critical. In this segment, Dave Maheu, VP, Head of Process & Analytical Development at Candel Therapeutics and Curran Simpson, Chief Operating Officer at REGENXBIO share what they consider to be the most difficult challenges in vector development and manufacturing currently.

  2. Scalable Purification Of In Vitro Transcribed mRNA 6/24/2025

    Learn more about how affinity-based mRNA chromatography resin facilitates the purification and isolation of mRNA from in vitro transcription (IVT) manufacturing processes.

  3. Expanding Manufacturing Of Purification Resins To Align With Customer Demands 7/15/2025

    Discover how scaling up processes and building out facilities has allowed for end-to-end solutions that meet customer requirements for both supply and quality in their production lines.

  4. Cytovance Customer Testimonial: Thermo Scientific Single-Use Technologies 12/8/2020

    Thermo Fisher Scientific has served as a key partner in the bioprocess industry, by establishing manufacturing and development capabilities, enabling Cytovance Biologics to expand offerings their product offering, to better serve clients with diverse pharmaceutical needs. In this video, the imPULSE Single-Use Mixer is highlighted for protein refolding applications at a 30 L scale and then transferred to manufacturing operations up to 5,000 L scale.

  5. Auto, Allo, And AI 8/18/2023

    CTO experts debate autologous and allogeneic, and how automation improves the CAR-T cell process every step from collection to infusion. They also discuss the major ways AI optimizes automation.

  6. Major Trends Impacting Allogeneic Cell Therapies For Oncology 5/6/2024

    We kicked off this Cell & Gene Live, Unlocking the Future of Allogeneic Cell Therapy for Oncology by discussing the major trends impacting allogeneic cell therapies for oncology.

  7. Efficient AAV Purification With AAVx And AAV9 Magnetic Beads 6/30/2025

    Explore an alternative to chromatographic affinity capture that eliminates the need for universal nuclease treatment by utilizing magnetic beads with ligands specific to AAV.

  8. The Need for Speed: Dr. Peter Marks and Dr. Nicole Verdun Explain Meeting Unmet Need for Pediatric Patients 1/30/2024

    How can sponsor companies accelerate development in pediatric patients for genetic diseases that affect both children and adults, but where gene therapy holds the greatest promise to address unmet needs in pediatric patients?

  9. Rapid Process Development And Technical Support For AAV Scaleup 12/17/2024

    Accelerate your AAV production journey. Learn how rapid process development and expert support can streamline your path from vial to purified bulk, ensuring scalable and efficient manufacturing.

  10. Key Considerations For Rapid Microbial Methods For Mycoplasma Detection 5/29/2025

    Learn the importance of demonstrating product specific suitability, defining representative sample, consistent sampling protocols, accommodating volume and turnaround time constraints, and the need to establish equivalence.