Industry Insights
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Liposome Drug Delivery: Global Trends & Market Forecast
1/19/2024
Liposomes possess the ability to encapsulate drugs of both hydrophilic and hydrophobic nature. They can be tailored to target tissues or cells, enabling precise drug delivery. Let's examine how it works, applications, and new market insights.
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Surmounting The Challenges To Realizing The Potential Of CGT For Neurological Disorders
1/18/2024
Incorporating innovative technologies, such as CRISPR/Cas9, and understanding the molecular basis of neurological disorders are crucial in shaping the future of gene therapy.
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Breaking Down Solid Tumors With Triumvira Immunologics' Dr. Paul Lammers
1/18/2024
Paul Lammers, M.D., M.Sc., CEO of Triumvira Immunologics joins Cell & Gene: The Podcast to talk to Host Erin Harris about TAC, the company's proprietary T cell Antigen Coupler, which has both autologous and allogeneic approaches. They also discuss targeting relapsed or refractory HER2-positive solid tumors and CLDN18.2-positive solid tumors. And they cover a realistic outlook on the evolution of cancer treatment.
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Exploring Epigenetics To Predict Type 2 Diabetes
1/18/2024
Epigenetic programming allows two genes with identical sequences to function differently. One crucial mechanism in this process is DNA methylation, involving the addition of a methyl chemical mark to specific gene positions. Environmental exposures in early life could potentially modify the DNA methylation of crucial genes responsible for regulating sugar and metabolism.
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Need To Improve Your Change Management? Regulators Can Help With That
1/12/2024
The path to successful change management in drug manufacturing can be pocked with bottlenecks. Here are some tactics you can use to avoid them.
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Is FDA’s COVID Container Closure System Guidance Useful Post-Pandemic?
1/9/2024
The COVID-era guidance is designed to help manufacturers make container closure system changes quickly when facing supply constraints. It may be useful when evaluating risks beyond the pandemic.
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Are Single-Use Technologies Always The Answer?
1/9/2024
It is clear that single-use technologies (SUTs) have won the war over reusable stainless steel. However, beneath the surface, there is a web of considerations that challenge the belief that SUTs are unequivocally cost-effective. Let's look at cost considerations as well as risk considerations.
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Cell & Gene Therapies: How Can Our Knowledge Of 2023 Inform Our Predictions For 2024?
1/8/2024
2024 promises a potential turnaround and blue skies for cell and gene therapies. Let’s explore each modality’s prospects: oligos and mRNA, cell therapies, and viral gene therapies.
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Tackling 3 Challenges In Developing An Inhaled Gene Therapy
1/5/2024
Inhalers hold great potential for delivery of high concentrations of gene therapy directly into the lung. This article shares the experiences of a team who have worked on the development of a gene therapy to treat cystic fibrosis.
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4 Keys To Allo In 2024 With Poseida Therapeutics' Kristin Yarema, Ph.D.
1/4/2024
Kristin Yarema, Ph.D., CEO, Poseida Therapeutics sits down with Cell & Gene: The Podcast Host Erin Harris to discuss four of the biggest challenges the CGT sector faces when it comes to the development of off-the-shelf therapies. Kristin shares how 2024 might see some real progress in allogeneic therapies.