Industry Insights

31. Questions You And Your New CDMO Might Be Asking 3/27/2025

    One expert who has been on both sides of contracting relationships explores common questions you could — or should — be asking before signing up with a new manufacturer.

32. The Importance Of Primary And Secondary Drying And Their Impact On Lyophilization 3/25/2025

    For parenteral formulations, biologics, and vaccines, the lyophilization process's primary and secondary drying stages require precise control of temperature, vacuum, and duration. 

33. Counting The Steps To Decentralized Personalized Therapy Manufacturing 3/21/2025

    AltruBio's CEO has a rough map of the steps to distributed cell therapy manufacturing. She discusses the path and some of the obstacles we'll need to clear first.

34. Upskilling Your Quality Team For The AI Revolution In Pharma 4.0 3/21/2025

    While AI systems offer advanced capabilities for data analysis, process optimization, and quality assessments, your quality team must first be proficient in interacting with them.

35. HLA Typing For HSCT: New Research Indicates Expanded Patient Compatibility 3/20/2025

    A challenge in hematopoietic stem cell transplantation (HSCT) is finding a fully matched unrelated donor. Recent advances in research and human leukocyte antigen (HLA) typing are allowing more patients to be matched.

36. Transforming Neurodegenerative Disease Research With iPSCs: A Path To Innovation And Therapeutic Breakthroughs 3/19/2025

    This article detailed why iPSC-based therapies offer promising yet experimental solutions for neurological disorders with early clinical studies demonstrating safety and potential efficacy, though long-term outcomes remain to be validated.

37. De-Risk Cytokine Release Syndrome With Digital Health Tech 3/19/2025

    Nearly 80% of patients undergoing CAR T cell therapy experience cytokine release syndrome, and Digital Medicine Society (DiMe) has the advice and resources to enable early detection and prediction.

38. A Practical Guide To Defining Priority Data In MES 3/17/2025

    Manufacturing execution systems (MES) play a crucial role in pharma/biotech, but MES platforms face the challenge of identifying the critical data that should be prioritized for supporting effective operations.

39. Applying AI To Identify Synergistic Drug Combinations For Cancer Treatment 3/14/2025

    By combining drugs/therapies with different mechanisms of action, different pathways in cancer cells can be targeted, potentially leading to improved patient outcomes. Using AI is hastening this research.

40. Collaboration Leads To CGT Progress At Astellas' West Coast Innovation Center 3/13/2025

    Yoshi Shitaka, outgoing CSO and Richard Wilson, SVP, Primary Focus Lead (Genetic Regulation) at Astellas share how the company's West Coast Innovation Center serves as a central hub for AI, digital transformation, and more.