Featured Articles

  1. Sterile Filtration And Quality Risk Management 8/31/2023

    Process control is essential for manufacturing sterile products. Explore the role of filtration for bioburden control in quality risk management and contamination control strategies.

  2. Outsourcing: Biomanufacturers May Need Consultants More Than Ever 7/27/2023

    When it comes to outsourcing drug development and manufacturing, are consultants important? Explore the role of consultants and industry trends that influence their relationships with organizations.

  3. The Colloidal Particle Adsorption (CPA) Model In IEX 7/13/2023

    Learn about an adsorption isotherm class that is based on a colloidal description of proteins and achieves increased accuracy at high column loading in IEX modeling.

  4. Controlling Trace Impurities In Chemically Defined Media 4/10/2023

    Discover a novel approach for manufacturing chemically defined media with precision control of trace impurities that utilizes innovative raw material analysis, data analytics, and a proprietary algorithm.

  5. LNP Formulation For mRNA Delivery 2/15/2023

    Microfluidic mixing is one of the most effective means to formulate LNPs for its scalability and reproducibility. Explore LNP formulation, polishing, sterile filtration of mRNA-LNPs, and more.

  6. mRNA Product Purification Process Strategies 2/15/2023

    Impurities from IVT can induce undesired immune responses and negatively impact translation efficiency. Explore the pros and cons of each option for mRNA purification.

  7. mRNA Product IVT Process Insights 2/15/2023

    In vitro transcription (IVT) allows a researcher to tailor synthesis and introduce modifications to produce a transcript. Learn about IVT along with process challenges and strategies.

  8. mRNA: Challenges And Strategies Related To The DNA Template Process 2/15/2023

    Encapsulated mRNA–LNP creation begins with synthesizing the DNA template. Explore insights on DNA template synthesis, the challenges and strategies of generating a DNA template using PCR, and more.

  9. Introduction To mRNA Manufacturing 2/15/2023

    The SARS-CoV-2 virus has changed the course of scientific research around mRNA. Learn about mRNA manufacturing, the structure of a mRNA molecule, RNase-free considerations, and more.

  10. A Guide To Polishing Chromatography In Process Development 2/6/2023

    Polishing chromatography describes the removal of minute amounts of impurities in the final phase of biopharmaceutical manufacturing. Explore considerations in developing your polishing steps.