Featured Articles

  1. Improve Sterile Drug Quality With Parenteral Filtration 1/30/2023

    Learn about large and small volume parenteral injectable drugs, their comparative sizes, types, sterilization processes, and applications.

  2. Magnetic Bead Removal Using Microcarrier And Cell Separation System 11/2/2022

    The FDA holds strict requirements for magnetic bead removal prior to therapeutic use. Learn how this system effectively separates cells from microcarriers and provides maximum cell recovery.

  3. How to Stay One Step Ahead Of Biopharma Supply Chain Constraints 11/2/2022

    Examine one company's solution to minimizing production delays despite the single-use supply constraints exacerbated by the COVID-19 pandemic that are interfering with bioprocess operations.

  4. Freeze/Thaw And Cold Chain Process Optimization 4/6/2022

    Freezing biologics is a complex undertaking. As more biotherapies enter the market, ensuring manufacturers have the technology to optimize their cold chain applications is paramount.

  5. Impact Of Scalable Freeze/Thaw Cycling On Protein Stability And Structure 12/21/2021

    The need for low-temperature storage capable of surmounting the molecular and logistical challenges associated with these treatments has become core to achieving commercial-scale production.

  6. Particulate Contamination Levels In Single-Use Systems 11/29/2021

    We investigate material adsorption of mRNA-encapsulated lipid nanoparticle (LNP) formulation comparing the Aramus fluoropolymer bag to commonly used glass vials and polypropylene (PP) cryotubes.

  7. Single-Use Bag Particle Testing To Ensure Surface Cleanliness 8/30/2021

    This application note explains the use a liquid particle counter to qualify the cleanliness of single-use 2D bag assemblies.

  8. Vendor Partnering In Bioprocess Manufacturing, Supply Chains 8/16/2021

    New single-layer assemblies, made without the curing agents, antioxidants, plasticizers, or adhesives that represent potential contamination sources, may offer companies a safer, more efficient choice.

  9. Single-Use Bags Compatibility With Dimethyl Sulfoxide (DMSO) 6/2/2021

    This application note reviews the chemical compatibility of Aramus™ assemblies with dimethyl sulfoxide (DMSO), which is commonly used as a cryopreservant in the cell and gene therapy (CGT) markets.

  10. Aramus Single-Use Bag Assemblies For Cryogenic Temperature Compatibility 6/2/2021

    This application note explores the cryogenic temperature compatibility of the Aramus™ bag assembly material through freezing and drop testing after 24-hour minimum immersion in the liquid nitrogen (LN2) vapor phase.