Featured Articles

  1. Small Volume ATMP Cryo-Freezing Strategies 3/11/2025

    Discover best practices for cryopreserving small-volume ATMPs, focusing on sterility, viability, and efficiency with advanced containers and packaging.

  2. Ask The Expert: Single-Use Technology In Cell And Gene Therapies 7/16/2024

    As CGT developers gain knowledge about their processes, single-use technologies (SUT) manufacturers can better address the sector's unique autologous needs by adapting to smaller volume production.

  3. Use Single-Use Connectors To Increase The Integrity Of Closed Systems 12/3/2020

    While single-use connectors can reduce many of the risks associated with tube welding, it is essential the ones you select meet the sterility and reliability needs of your application.

  4. Effectively Securing CGT With Closed Systems 2/5/2020

    Enhance your cell and gene therapy manufacturing with single-use connectors, an easy-to-use method for flow path sterility and integrity during manufacturing that also prevents costly contamination failures.

  5. Why Is E&L Testing Important For Single-Use Connectors? 7/2/2019

    A critical issue when transitioning from stainless steel to plastic equipment is the presence of extractables and leachables (E&L). See how BPOG testing on single-use connectors mitigates the risks.

  6. How To Overcome Validation Challenges In A Single-Use World 9/7/2017

    How can end users ensure the expected level of compliance in this new world of single-use systems? The secret: shared responsibility for validation with your supply chain.

  7. Implementing Global Best Practices For Single-Use Systems

    Single-use technology has only been used at manufacturing scale for about 10 years. Relative to other technologies, single-use systems are new and experience can be limited. 

  8. Genderless Single-Use Connectors Make For Easier Systems Design, Flexible Process Flow

    Colder’s John Boehm tells Pharmaceutical Online’s Lori Clapper about the evolutions of single-use technologies and the trend towards downstream processes.  He discusses how, in the growing demand and adoption of single-use technologies, the unit operations are incorporating more single-use systems whether its bag systems and tubing assemblies. However, as they get larger and larger, it is difficult to sterilize those in one large piece. So they are typically broken down into individual units. The key to having a completely single-use system, or even a hybrid system, is you have got to bring those systems together. Colder has responded to this challenge by creating the AseptiQuik G connector (G for “genderless”) to create process flexibility for the end user.

  9. The Benefits Of Converting To Single-Use For Bioprocessing Systems

    Single-use is an inexpensive and flexible way to bring that product into the process, yet the value of that product was low enough that they were willing to take a risk on a new technology.

  10. How To Choose The Right Connector For Your Biopharm Application

    With so many connection options, it can often be an overwhelming task to decide which connector is best suited for a specific application. By understanding your application requirements and selecting the correct connection type, you will have better performance and sealing results.