FEATURED ARTICLES

• Cell And Gene Therapy Collections: The Need For Consistency

  From donor variability to collection site inconsistencies, cell and gene therapy faces raw material challenges. Ensuring stable, high-quality leukopaks is vital for effective treatments.

• How The Cell And Gene Therapy Market Is Taking Shape

  Targeting diseases at their genetic root, cell and gene therapies offer unprecedented hope. Yet, the industry grapples with balancing groundbreaking potential against the challenge of high-priced treatments.

• How AI Is Streamlining Cell And Gene Therapy Manufacturing

  Learn how AI, powered by quality data and real-time monitoring, is accelerating production and bringing life-saving treatments to more patients.

• Reflecting On A Milestone Year For Cell And Gene Therapies

  Examine the significant CGT advancements in 2024, including new approvals for solid tumors and diabetes treatments, as well as the role of AI and logistical improvements in scaling these therapies.

• Streamlining Mesenchymal Stem Cell (MSC) Expansion

  A new functionally-closed cell expansion system featuring a hollow-fiber membrane and customizable protocols is streamlining the production of stem cells for regenerative medicine.

• Calls For Increased Education And Support For Sickle Cell Blood Therapy In US

  Sickle cell patients face limited access to effective treatments. Advocacy groups are pushing for greater awareness of innovative therapies like apheresis to improve outcomes and address resource gaps.

• Gamma Delta T Cells Explained: The Next Medical Breakthrough?

  Gamma delta (γδ) T cells are emerging as a promising new frontier in cell therapy, offering potential for treating both solid tumors and autoimmune diseases.

• Ways To Enhance Access To Cell Therapies

  Cell therapies are revolutionizing cancer care, but their complex manufacturing and high costs bar access for many patients. Automation is emerging as an efficacious solution to reach patients in need.

• Expansion Of Cord Blood-Derived CD34+ Cells In A Hollow-Fiber Bioreactor With 10% Standard Cytokine Concentration

  CD34+ cells isolated from cord blood were expanded in a hollow-fiber bioreactor using a novel cytokine cocktail at one-tenth the standard concentration using a MSC-free coating strategy.

• Navigating The Challenges Of Bringing Cell And Gene Therapies To Market

  Cell and gene therapies are witnessing rapid advancements, but significant challenges remain for their commercialization due to regulatory hurdles, manufacturing barriers, high costs, and safety concerns.

• T-Cell Manufacturing: When Is The Right Time To Automate?

  Automation enhances efficiency and minimizes contamination risks and labor costs. Despite the initial investment in automation equipment, the long-term savings can be significant.

• How Cell And Gene Therapies Are Evolving

  Advances in manufacturing technologies and equipment are improving the efficiency and reproducibility of cell and gene therapies and helping overcome the current supply and demand imbalance.

• Harnessing The Power Of Cell And Gene Therapy In Oncology

  Advances in oncology, specifically in CAR T-cell therapies and TILs, are leading the way in cell and gene therapy. However, costs and complex regulations present challenges.

• Quality Versus Quantity In T-Cell Production

  Technological advances have made it possible to produce high-quality T cells at scale, providing a boon for T-cell manufacturing.

• iPSC Expansion In A Cell Expansion System's Small Bioreactor

  Explore how using a flexible, automated system can help expand induced pluripotent stem cells (iPSCs) faster than traditional culture methods.

• Cell Expansion System Supports Proliferation Of Regulatory T-Cells

  This study showcases a cell expansion system that is providing T-cells with an ideal environment for growth, efficient in expanding many cells quickly, and enhancing regulatory T-cell characteristics.

• HEK293T Cell Expansion Protocol Using A Hollow-Fiber Bioreactor System

  Explore the use of a hollow-fiber bioreactor (HFB) system for the automated expansion of HEK293T cells and a protocol used to help users of the system.

• Study Of Small Bioreactor Expansion Kinetics During Expansion Protocol

  Mesenchymal stem cells have been used to show equivalent expansion kinetics during a 7-day expansion protocol on both the small and standard bioreactors revealing efficiency differences.

• Quintessential Role Of Apheresis In Gene-Modified T-Cell Therapy

  Learn more about process standardization and comprehensive quality management programs as it relates to leukapheresis and cell therapy manufacturers.

• Choose The Right Bioreactor Size For Your Cell Expansion

  Compare expansion parameters when adherent cells are cultured on the small and standard bioreactors using a hollow-fiber bioreactor platform.