06.03.25 -- Will Genome Modifications Define Next-Gen AAV Vectors?

Scaling up life-saving gene-edited cell therapies means tackling production inefficiencies. Overcoming the time-consuming and risky cell washing step is crucial for clinical and commercial success.

Designed to enable efficient scalability, a new FBR platform allows operators to use one technology, with a standardized workflow, for their process development, scale-up, and manufacturing processes.

Explore an innovative serum-free method to differentiate induced pluripotent stem cells (iPSCs) into natural killer (NK) cells, offering scalable solutions for immunotherapy with enhanced cytotoxic potential.

Chromatography resins are aiding in the delivery of cancer and inflammatory disease therapies. Learn how ion exchange resins act as therapeutic carriers for advanced drug delivery.

Learn how AI, powered by quality data and real-time monitoring, is accelerating production and bringing life-saving treatments to more patients.

Optimizing in vitro transcription (IVT) for mRNA is crucial to improving the stability of these molecules and enabling their large-scale production.

Use microchip CE-MS technology to achieve quicker peptide mapping analysis, high sample reproducibility, and low artificially induced modifications.

Knowledge of the feed stream, process constraints, and goals, makes selecting depth and membrane filter combinations for preliminary bench-scale filterability studies possible.

Advanced therapies present challenges when it comes to scaling up production. Explore how collaboration, investment in R&D, and process optimization are paving the way for new treatments.

NGS-based methods for agnostic broad range detection are suitable options to augment or replace current virus testing methodology. Explore a NGS AAT method for cell line characterization and more.