By Georgius de Haan and Nadia Kadi
Many techniques in Life Science research rely on efficient filtration during sample preparation. The use of filter plates has allowed simultaneous filtration of multiple samples by means of centrifugation, vacuum, or positive pressure. Until recently, this methodology was mostly available for high throughput of smaller sample volumes with the aid of 96-well or 384-well filter plates whereas processing of larger sample volumes was relegated to the use of, for instance, centrifugal devices or syringe filters. The latter devices are capable only of handling individual samples, complicating simultaneous processing of multiple samples. Pall has recently introduced a family of 24-well filter plates which allow simultaneous processing of samples with volumes of up to 7 mL, for applications as depth filtration/clarification, (sterile grade) microfiltration, and ultrafiltration, thereby providing options to streamline a wide variety of workflows for medium throughput high volume sample preparation methodologies depending on filtration.