Application Note

Strategy For The Development Of A Manufacturing Process Of Single Domain Antibody (sdAb)

Source: Polyplus
Antibodies GettyImages-512051390

This application note provides an extensive process development approach for establishing an optimized manufacturing protocol for producing single-domain antibodies (sdAbs) for therapeutic use. It covers the development of microbial expression strains, optimization of upstream and downstream processes, and formulation development, aiming to achieve high-quality (HQ) and good manufacturing practice (GMP) grade production.

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Polyplus