Single Cell Isolation With Minimal Input

Efficient isolation of single cells is a critical step for single-cell genomics, cell line development, and more. Traditionally, researchers have relied on cell sorters to isolate individual cells for these applications. However, aside from their pitfalls as high maintenance and operationally complex machines, traditional cell sorters also require cell samples to travel through long sample tubing, resulting in a high dead volume. To compensate for such loss, a large initial sample input is required. For precious cell populations, including primary or clinical samples, meeting this high sample input requirement can be impossible.

Namocell’s single cell dispensers use disposable, microfluidic cell cartridges into which samples are directly loaded. As the sample flows through the cell cartridge, a proprietary mechanism sorts and dispenses cells within the cartridge in a single step, thus dramatically reducing the dead volume as compared to traditional cell sorters. Read about our evaluation of the single cell isolation efficiency of Namocell’s Hana Single Cell Dispenser with a low sample input of only 100 cells with both adherent and non-adherent cell lines.