Newsletter | July 9, 2025

07.09.25 -- Rethinking Academic Translation In CGT: Inside The RISE Framework At Mass General Brigham

SPONSOR

Webinar: Revolutionizing Cell Metabolism Monitoring: Inline, Real-Time Glucose and Lactate Analysis

This PHC webinar explores how real-time, inline monitoring of glucose and lactate using PHCbi’s LiCellMo® technology can transform bioprocessing and cell therapy. Learn how continuous metabolic analysis improves cell viability, reduces variability, and accelerates decision-making—overcoming the delays and inconsistencies of traditional sampling methods to enhance product quality in biopharma, regenerative medicine, and academic research.

FOCUS ON TRANSLATIONAL RESEARCH

Rethinking Academic Translation In CGT: Inside The RISE Framework At Mass General Brigham

The RISE framework — focused on Resource sharing, Interdisciplinary collaboration, Sustainable funding, and Educational outreach — is helping academic medical centers such as Mass General Brigham overcome translational barriers in cell and gene therapy development and bring promising therapies closer to clinical application.

Factors Influencing CD34+ Cell Collection Efficiency In Leukapheresis

Efficiently collecting sufficient peripheral blood stem cells is paramount for successful transplantation, necessitating a deeper understanding of influencing factors and procedural nuances.

Advancements In Genome Integrity Assessment For Gene Therapies

Gene therapy holds promise for treating various genetic diseases. Explore the latest in gene therapy with expert insights on AAV vector integrity, dPCR-based solutions, assay design, and reference standards.

A Study To Assess Organoid Size And Cell Count From 3D Image Analysis

Recent advancements in 3D patient-derived organoids (PDOs) offer predictive power over traditional 2D assays. Explore a patented bioprocess for PDO expansion that could revolutionize drug discovery.

Exploring RNA Structure And Ligand Interactions With MMS

Explore how microfluidic modulation spectroscopy (MMS) reveals RNA base pairing and lipid adduct effects, offering insights into RNA-ligand interactions and structural changes in solution.

Electroporation Powers Scalable CRISPR-Cas9 RNP Packaging In VLPs

Discover how electroporation technology enables efficient, scalable production of CRISPR-Cas9 VLPs with high editing activity in both adherent and suspension HEK293 cells.

CHO Cell Biocompatibility In X-ray Irradiated BioBLU Bioreactors

In cell culture, the leakage of toxic or inhibitory chemicals from single-use bioreactors has become a growing concern. Explore recommendations for leachable studies.

Simplifying EV/Exosome Research & Development

Modern solutions are continuing to be developed to help those working in biologics overcome historic Exosomes / Extracellular Vesicles challenges.

How Automation And AI Can Accelerate Clinical Research And Outbreak Response

AI and organ-on-a-chip tech accelerate infectious disease research, boosting assay efficiency and advancing vaccine and therapeutic development for global health threats.

SPONSOR

Webinar: Improving Quality Control: Tackling Residual DNA Testing in Biotherapy Manufacturing

Explore how to strengthen quality control in biotherapy manufacturing with advanced residual DNA testing in this webinar from Thermo Fisher Scientific. Learn why residual DNA testing is vital for product safety and compliance, uncover common challenges and misconceptions, and discover how molecular-based methods can enhance accuracy, sensitivity, and reliability in your QC workflows. Click here to learn more.

TRANSLATIONAL RESEARCH SOLUTIONS

Thermal Ramping Characterization Solution: Aurora TX - RedShiftBio

High-Content Flow Cytometry - Precision for Medicine

BD FACSLyric Flow Cytometry System - BD Biosciences

Cell Therapy: Streamline The Path From Discovery To Commercialization - Thermo Fisher Scientific

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