Newsletter | April 9, 2024

04.09.24 -- Reducing Toxicities In Allogeneic Cell Therapies

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Webinar: Safety at the Center – The Synergistic Role of Drug Safety in Clinical Trial Operations

In drug safety and pharmacovigilance, collaboration isn't just a buzzword—it's an essential component that can impact patient safety and the success of your product. Join us in this webinar as we highlight the importance of effective interpersonal leadership in your drug safety program and reveal the operational and financial efficiencies that can result from a collaborative dynamic. Click here to learn more.

FEATURED EDITORIAL

Reducing Toxicities In Allogeneic Cell Therapies

Orca Bio's CMO, Dr. Scott McClellan, joins Erin Harris on Cell & Gene: The Podcast to explore persistent toxicities in allogeneic cell therapies. They discuss Orca Bio's strategies to reduce GvHD risks and Orca-T, an advanced allogeneic cell therapy under clinical evaluation for treating various hematologic malignancies.

INDUSTRY INSIGHTS

Tips For Designing A Single-Use Manifold For Advanced Therapies

Expert single-use engineers address six common questions posed by cell and gene therapy manufacturers in the design of custom single-use manifolds for the critical handling of biological fluids.

Top 3 Megatrends In OT Cybersecurity

Explore the megatrends that are shaping the future of operational technology (OT) cybersecurity and the strategic measures organizations can take to protect themselves against threats.

The Latest Solutions To Improve Your CAR T Cell Research

Learn how to isolate fully functional T cells directly from whole blood and blood products, boost lentiviral T cell transduction efficiency, easily activate and expand your T cells, and advance your IPC and QC.

Cleaning And Disinfection Protocols For Annex 1

The new GMP regulations coming out of the European Union will have a big impact on pharmaceutical manufacturers. Learn about executing a CSS, cleaning, disinfection, and much more.

In-House Manufacturing: Key To Driving A Diabetes Vaccine?

Increasing constraints on today’s supply chain from the COVID-19 pandemic mean drug companies must secure strategies that can ensure product delivery in the face of these challenges.

Lentiviral Vector Bioproduction Follow-Up Tool

Explore a new optical device that performs real-time, user-friendly, and label-free measurements of lentiviral vector physical titer and size distribution.

Alofisel P3 Cell Therapy Facility

Despite various issues with a client's CQV project, CAI delivered the project on time and significantly contributed to the delivery of the first ATMP facility in Ireland.

4 Factors To Consider When Scaling Up

It's essential to understand how scaling up affects your aseptic filling operations. Here are four topics to consider to help ensure your drug product will be taken care of and ready for production.

Analyzing Serum-Free Media For Cell Therapy Applications

Identifying critical factors and their concentrations with an eye towards designing an ideally formulated, defined serum-free medium should be carried out using rational and systematic approaches.

Single-Cell Dispensing, Screening Of Cell Lines For Monoclonality Verification

Use the impedance-based single-cell dispenser and high-throughput fluorescence-based imager to optimize editing, dispensing, and screening during the monoclonal cell-line development process.

Regulatory CMC Considerations For Biotherapeutics And Cell And Gene

Follow along as Regulatory CMC from Veristat covers critical topics related to CMC regulations, addressing challenges, outlining strategies, and highlighting considerations for analytical programs.

SOLUTIONS

SciVario twin Bioprocess Controller Brochure

Optimize Quality And Compliance With End-To-End Training Solutions

Spent Media Analytics: Unlock New Process Insights

Benzonase Endonuclease Safety Plus Emprove Expert

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