Article | January 23, 2025

Optimized Production Of Recombinant Proteins

GettyImages-517653042 bioreactor

The biopharmaceutical industry is experiencing rapid growth, driven by the increasing demand for biologics like monoclonal antibodies. These complex therapeutics require sophisticated manufacturing processes to ensure high quality and efficacy. Optimizing cell culture media is crucial for achieving these goals, as media components directly impact cell growth, productivity, and the critical quality attributes of the final product.

This article explores the intricate relationship between cell culture media, specifically amino acid levels, and the production of recombinant proteins. We delve into how variations in amino acids can affect protein yield, glycosylation patterns, and other key factors influencing therapeutic efficacy. Discover how at-line amino acid analysis offers a solution to these challenges, enabling real-time monitoring and optimization of cell culture media for improved biopharmaceutical manufacturing.

Read the full article to learn more about the role of amino acids in recombinant protein production and the benefits of at-line analysis.

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