Newsletter | November 13, 2024

11.13.24 -- Neogene's Focus On Off-The-Shelf TCR Therapies

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Despite significant advances, challenges remain in optimizing AAV-based treatments for broader clinical application. Join Cell & Gene Live on December 10th for a discussion on the latest developments in AAV vector design, manufacturing processes, and clinical strategies as well as key issues such as immunogenicity and regulatory considerations that are shaping the future of AAV gene therapies. Registration is free thanks to the support of Roche CustomBiotech.

FOCUS ON TRANSLATIONAL RESEARCH

Neogene's Focus On Off-The-Shelf TCR Therapies

This recap of Episode 87 of Cell & Gene: The Podcast shares Neogene Therapeutics' Carsten Linnemann, Ph.D.'s take on why "off-the-shelf" will make t-cell receptor therapies more accessible to patients.

How To Evaluate And Compare Real-Time PCR Reactions

Learn about the key factors that influence qPCR reaction performance and provides guidelines for evaluating and comparing reactions run under varying conditions to ensure reliable data interpretation.

Cell Therapy Milestones, Challenges, And Forming The Future Of TILs

What enabled the evolution of TIL therapies? What does the future hold for them? And where should you concentrate your efforts to accelerate progress? Watch for answers to these questions and more.

In Vitro Potency Assay Development For SHANK3 AAV Gene Therapy

Discover how JAG201, an innovative AAV9-based gene therapy, transforms the treatment landscape for patients with Phelan-McDermid syndrome and SHANK3 haploinsufficiency.

Cell And Gene Therapies – Global Clinical Trial Landscape (2024)

The landscape of cell and gene therapy is advancing rapidly, revolutionizing healthcare by offering novel treatments for cancer, rare genetic conditions, and hematological diseases.

Role Of Early Characterization In Assessing Therapeutic Potency

Early product characterization can serve to uncover crucial information about an advanced therapeutic candidate, affording new insight into its CQAs and helping to shape better analytical assays.

Unlocking The IP Benefits Of Novel Nucleases In CRISPR Therapies

Incorporating novel nucleases into CRISPR therapies enhances intellectual property benefits through improved licensing, strategic protections, and access to new gene targets.

The State Of CRISPR And Gene Editing Presentation

Listen in on this session from The State of CRISPR and Gene Editing Summit which focus on the use of CRISPR-based therapies in clinical settings using electroporation. 

How mRNA Technology Engineers Next-Generation Antibodies

Monoclonal antibodies (mAbs) stand as pivotal drug products and biochemical reagents in the 21st century. Explore how mRNA-encoded antigens could revolutionize antibody discovery.

Advancing 3D Cell Culture Models For Clinical Relevance

Concerns about in vitro relevance and animal study limits have advanced cell culture tech. Consider how Organ-Chips offer a refined approach to studying human physiology.

Automated Setup And Compensation On BD FACSLyric Streamlines Workflow

Examine the usability and performance capabilities of a system that provides a streamlined flow cytometry workflow, from instrument initialization to data acquisition and analysis.

Maximizing The Value Of Your AAV Using Small Volume AAV Testing

Learn about an approach to method development, where more than one AAV critical quality attribute can be measured within a single analytical run.

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Webinar: Innovative AI Software Solutions Driving Biomarker Research Efficiency

Biomarker discovery and validation are critical, but the complexity of high-throughput assays and image-based analyses presents significant challenges in extracting meaningful insights efficiently. Please join us at this webinar to explore how cutting-edge platforms and software are transforming biomarker studies. By harnessing the power of innovative solutions you can overcome traditional bottlenecks, reduce time to insight, and improve the overall efficiency of your biomarker research.

TRANSLATIONAL RESEARCH SOLUTIONS

BD FACSLyric Flow Cytometry System - BD Biosciences

Chip-R1 Basic Research Kit - Emulate

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