Newsletter | August 14, 2024

08.14.24 -- Manufacturing CAR-T In Vivo

SPONSOR

Don't miss the next Cell & Gene Live discussion on how CAR-T manufacturing has advanced recently and where it's going. Host Tyler Menichiello welcomes CTMC's Jason Bock, Ph.D., Cartesian Therapeutics' Emily English, Ph.D., and former FDA-turned Dark Horse consultant and CMC Expert, Tal Salz, Ph.D., for this digital event happening Tuesday, August 27, at 11 AM ET. Registration is free thanks to the support of CPC.

FROM THE EDITOR

Manufacturing CAR-T In Vivo

Manufacturing chimeric antigen receptor (CAR) T-cell therapies is a costly and complicated process. Interius BioTherapeutics is on a mission to reduce this complexity and get these therapies to patients faster — by manufacturing CAR T/NK cells in patients' bodies.

FEATURED EDITORIAL

Inside Next-Gen Platforms For Cell Therapy Manufacturing | Audience Q&A

In one of our most active Cell & Gene Live audience Q&As to date, Will Junker and Nick Siciliano responded to several audience questions ranging in scope from reducing environmental control requirements with respect to total COGs for cell therapy manufacturing to the technologies that benefit in closing of processes.

INDUSTRY INSIGHTS

A Focus On Cell Therapy: CAR-T, CAR-NK, And Beyond

As the landscape of CAR T-cell therapies evolves, these treatments are becoming more precise in targeting cancer cells and overcoming production challenges, and are poised to revolutionize oncology.

Optimizing And De-risking Your mRNA Product Manufacture

mRNA therapy and vaccine manufacturing can become complex and challenging when working with multiple CMOs. Partnering with an end-to-end CMO is key to overcoming these challenges.

Navigating Challenges In Progressing Breakthrough RNA Therapeutics

RNA therapeutics hold immense promise for precision treatment, but their development faces challenges. A CDMO with adaptable platforms and flexible timelines can help reduce time and costs.

Analytical Considerations For mRNA-Based Therapies

Uncover why leveraging strong scientific expertise and comprehensive testing techniques will be vital in expediting development and upholding the integrity of these life-saving treatments.

The Role Of Early Characterization Studies In Assessing Therapeutic Potency

Early product characterization can serve to uncover crucial information about an advanced therapeutic candidate, affording new insight into its CQAs and helping to shape better analytical assays.

Successful Clinical Manufacturing Of Cell And Gene Therapies

While biotech companies face pressure to rush to trials, development still requires a significant amount of work. This panel explores the pitfalls for developers and indicators of GMP readiness.

Biotechnology: The Key To America's Next Manufacturing Revolution

Learn how a recent expansion into Western Pennsylvania is aiming to enable more biopharmaceutical firms to translate cutting-edge science and research into practical applications.

SOLUTIONS

Cell And Gene Therapies – Changing The Healthcare Landscape

The Andelyn Difference: Making Gene Therapies Feasible For Patients

GS Effex Cell Line For Enhanced Antibody Effector Function

Helping Cell Therapy Innovators Bring Treatments To Market

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