MACS® GMP Recombinant Human IL-15
IL-15 is a member of the four α-helix bundle cytokine family. It is produced by different cell types, including epithelial cells, monocytes, muscle, and placenta cells. In addition to its ability to activate T cells and NK cells, IL-15 is also important for B cell growth and immunoglobulin production as well as for the maintenance of CD8+ memory T cells. For binding and signaling IL-15 uses the unique IL-15 receptor α-chain but shares the β- and γ-chain of the IL-2 receptor.
Interleukin 15 (IL-15) is a potent lymphoid cell growth factor and stimulates the proliferation of activated T cells and the generation of cytotoxic T lymphocytes (CTLs). IL-15 also induces the generation, activation, and proliferation of NK cells.
MACS GMP Recombinant Human IL-15 is designed for ex vivo cell culture processing. No animal- or human-derived materials were used for the manufacture of this product unless otherwise stated in the respective Certificate of Origin. The product is lyophilized without carrier protein or preservatives.