Newsletter | August 26, 2025

08.26.25 -- Lean Manufacturing Implementation In Pharmaceutical Injectable Facilities

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FOCUS ON MANUFACTURING

Lean Manufacturing Implementation In Pharmaceutical Injectable Facilities

This comprehensive analysis examines lean manufacturing implementation challenges and evidence-based solutions derived from leading pharmaceutical organizations. 

Phobic Vs. Philic: How The Process Indicates The Membrane In Bioprocess Applications

Some membranes attract water ("hydrophilic"), while others repel it ("hydrophobic"). Here, we examine which is best for your application.

The Role Of Cell Culture Media Growth Factors

Growth factors in cell culture media are essential for cell survival and behavior. Uncover their diverse roles and the science behind choosing the right ones.

Viral Vector Manufacturing Using Tangential Flow Depth Filtration

Address the rising gene therapy demands with an innovative perfusion strategy that significantly boosts cell density and viral vector yields to pave the way for scalable, efficient manufacturing.

Cell Line Development Tools For Rapid Prototyping

Discover rapid prototyping tools for cell line development, optimize clone selection, and learn how modern technology reduces process risks to enhance your capabilities with the latest advancements.

Scaling Up For Cell And Gene Therapies

Explore cutting-edge bioreactor strategies and overcome the challenges of large-scale production, including hydrodynamic conditions, media costs, and process reproducibility.

Finding The Right Aseptic Processing Approach

How should you approach building your aseptic processing line? Gain insight into the advantages of using a modular, configurable technology rather than custom fill-finish solutions.

Optimizing Production And Purification In AAV-Based Gene Therapy Manufacturing Workflow

Explore strategies for optimizing AAV gene therapy manufacturing. Discover solutions for scaling production, enhancing purification, and improving analytical methods to accelerate therapeutic development.

A High-Throughput Platform For Fast And Reliable Clone Screening

The Cydem VT platform consists of several technologies allowing for the cultivation and monitoring of CHO cells in cell line development. Find out how to set up your experiment on this device.

Tackling Encapsidated Host Cell DNA To Improve Quality

Discover a cell line that enhances rAAV production by reducing host cell DNA encapsidation, improving safety and efficiency through genetic modifications that inhibit apoptotic DNA fragmentation.

Universal AAV Enhancer For Better Titers, Quality, And Lower Costs

AAV therapies require high quality and high titers of viral genomes per dosage, prompting the need for a more efficient AAV manufacturing method to reduce overall costs.

MANUFACTURING SOLUTIONS

A Revolutionary Single-Use Rocking Bioreactor System - Cytiva

Imperforate Tubular-Bowl Centrifuge For Liquid-Solid Separation - CARR Biosystems

On-Line Glucose And Lactate Analyzer - Repligen – PAT

Project Management Process During A Mobile cGMP Compliant Facility Build - Germfree

Sterility Testing For Cell Therapy Bioproduction Samples - Thermo Fisher Scientific

EVENTS

Advancing the Future of Cell & Gene Therapy

This 11-12 November, Cell 2025 unites 1,000+ leading experts across the CGT value chain to solve key challenges, from scalable bioprocessing and regulatory hurdles to accelerating development timelines.

 

Gain practical strategies across cell culture, therapy development, and CGT manufacturing, and hear from world-renowned leaders Bobby Gaspar (CEO, Orchard Therapeutics), Christof Von Kalle, (Director & BIH Chair, Research Clinic Luxemburg), and Dame Molly Stevens (University of Oxford). Register Now

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