Optimizing Production And Purification In AAV-Based Gene Therapy Manufacturing Workflow

Adeno-associated virus (AAV) vectors have become a leading delivery platform in gene therapy due to their high biosafety, low immunogenicity, and ability to sustain long-term transgene expression. However, the high cost and complex manufacturing processes of AAV products currently limit their accessibility. This eBook explores strategies to enhance AAV manufacturing, highlighting innovative solutions for scaling upstream production and optimizing downstream purification, crucial steps for commercializing gene therapies.

Additionally, it features recent research on improving yield through high-binding capacity purification resins and efficient quantification methods. Delve into this guide to discover powerful resources and insights that can accelerate your AAV manufacturing efforts and improve accessibility to these vital therapies.