Large-Scale Exosome Production Stirred-Tank Bioreactors

Traditional cancer therapies often cause severe side effects due to their lack of specificity in targeting cancerous cells. This challenge highlights the critical need for more precise drug delivery methods. This study investigates the promising approach of loading cytotoxic drugs, like doxorubicin, into purified exosomes for targeted delivery to breast cancer cells. By genetically engineering exosomes to display tumor-penetrating and -targeting peptides, researchers aimed to enhance delivery efficiency and minimize harmful side effects.

The success of this strategy hinges on the ability to produce large quantities of these engineered exosomes, which was a key focus of this research. Read the full case study to delve into the methodology and results of this innovative approach.