08.20.24 -- Inside Next-Gen Platforms For Cell Therapy Manufacturing

Plasmids, essential in biologics manufacturing, pose challenges in their development and scale-up due to difficulties integrating and optimizing them with the appropriate cell lines during process development.

How did we arrive at neurological cell therapy solutions? Dr. Ole Isacson explores the stem cell steppingstones — from blood transfusions to Parkinson’s Disease treatments.

Consider several key points outlined in this article when deciding if a functional service approach could better serve a clinical team and its drug development study.

In Best Practices for Outsourcing Process Development, a panel of experts discussed four themes that may help drive the best outcomes when vetting process development service providers.

Watch to explore the relationship between a Contamination Control Strategy (CCS) and the development of a robust cleaning and disinfection program for cleanroom environments.

As CGT developers gain knowledge about their processes, SUT manufacturers can better address the sector's unique autologous needs by adapting to smaller-volume production.

Review the processes and best practices applied at a GMP facility to optimize the production of working virus seed stocks and master virus seed stocks.

Learn about the role of single-use technology in advanced therapy manufacturing, why pharmaceutical manufacturers are switching to disposable technology, and more.

Concerns about in vitro relevance and animal study limits have advanced cell culture tech. Discover how Organ-Chips offer a refined approach to studying human physiology.

Here, we outline a holistic approach to streamline the change control process, aiming to increase efficiency and compliance, improve quality, and shorten time-to-market.

This collection of articles explores the role of genetic engineering in understanding, preventing, and treating genetic diseases.

See how a bioprocessing company supplemented their in-house bioreactor capacity and performed large-scale DOE studies using a cloud bioreactor facility.

mRNA are singled-stranded, and their chemistry makes them more susceptible to enzyme degradation. Get tips for maintaining a nuclease-free environment during production and purification.