In Vitro Immunogenicity

The success of biologic drug development is often tempered by antidrug antibodies that can lead to unwanted immune responses. A crucial factor in the successful development of therapeutics is early immunogenicity prediction. In vitro assays offer many benefits for this early immunogenicity prediction, and primary cells are a necessary component of such assays. Thorough planning with standardized and high-quality cellular material can lead to more reliable results.