Hospital Researchers Turn To Corning To Help Scale Up Ex Vivo Expansion Of Adipose Stem Cells

Copenhagen University Hospital researchers turn to Corning for help scaling up ex vivo expansion of adipose stem cells to test the effect and reliability of a new procedure for breast reconstruction.

Autologous fat grafting is the least invasive method for breast reconstruction, but also has major drawbacks, including high tissue resorption rates of up to 80%. Researchers in Denmark, led by Prof. Krzysztof Drzewiecki, Department of Plastic and Reconstructive Surgery and Dr. Anne Fischer-Nielsen, Department of Clinical Immunology, Rigshospitalet, had a hypothesis: what if you could enrich the human fat graft with autologous adipose stem cells (ASCs) to increase graft survival? But they faced a major obstacle: how do you culture a sufficient volume of stem cells to increase grafting success? Dr. Peter Glovinski, leader of the present clinical study, turned to Corning, who designed a scale-up solution that’s enabling them to grow the billions of stem cells required to move forward with this clinical study.