High Throughput Bioreactor Considerations For High-Rise Gene Therapy Facilities

In urban laboratory facilities, the growing expansion of gene therapy research presents a significant opportunity for high-throughput bioreactor applications. Recent advancements in bioreactor automation have improved lab efficiency and provided a critical experimental advantage in early discovery and process development work. These high throughput bioreactors can simultaneously reduce risk and increase the potential for greater scalability in the run-up to full manufacturing process designs.

While the use of high-throughput bioreactors offers numerous performance and lab configuration advantages, the integration of bioreactors in these laboratories presents two key challenges from a design standpoint - limited space and building code limitations. In an urban setting, space availability can limit laboratory footprint configurations, placing a premium on equipment layout efficiency. Moreover, building code restrictions present a considerable challenge in providing a continuous and reliable supply of high-purity oxygen for bioreactors. This article will explore the interrelationship of high-rise laboratory design applications as they apply to bioreactor use.