Guidance For Pass-Throughs In cGMP Cell And Gene Therapy Facilities

By Carol Houts , VP Quality-Regulatory, Germfree

Cell and gene therapy facilities require stringent material control measures to prevent contamination and ensure patient safety. In traditional pharmaceutical facilities, large material airlocks act as an intermediate space between cleanrooms or between a cleanroom and a non-controlled environment. Active purging pass-throughs can help reduce the risk of contamination in facilities requiring containment along with other benefits.

Here we discuss how active purging pass-throughs offer an even higher level of material control for cell and gene therapy facilities by minimizing the need for personnel to enter and exit controlled environments, providing a highly controlled environment for material transfer, and supporting the protection of product.