Newsletter | August 6, 2025

08.06.25 -- From Discovery To Delivery: Accelerating The Path Forward For Gene Therapies

SPONSOR

Webinar: Breaking Barriers with PCR: Innovative Solutions for Clinical Trial Success

Designing PCR-based testing strategies for clinical trials requires not only technical precision but also thoughtful decisions around assay selection, platform capabilities, and clinical relevance. Join experts from Precision for Medicine, as well as guest speakers from Avidity Biosciences and Indaptus Therapeutics, as they explore how PCR-based molecular monitoring drives smarter, faster, and more efficient personalized clinical trials. Register Now

FOCUS ON TRANSLATIONAL RESEARCH

From Discovery To Delivery: Accelerating The Path Forward For Gene Therapies

We caught up with Lexeo Therapeutics’ Manny Otero, Ph.D., and Sandi See Tai, MD, to explore strategies to advance gene therapies.

Multiplexing In Real-Time PCR Experiments

Discover the capabilities of qPCR multiplexing. Delve into the principles of qPCR multiplexing, highlighting its efficiency in detecting and quantifying multiple genetic targets within a single reaction.

The LATAM Advantage

Julio Martinez-Clark, CEO of bioaccess, highlights the benefits of conducting clinical trials in Latin America, including lower costs, faster patient recruitment, and access to treatment-naïve populations.

Triplex RT-dPCR Method For A Safety Study In Drug Development

Discover how an innovative technology harnesses natural RNA editing with EONs and digital PCR to precisely correct mutations, which offers a novel approach to treating genetic diseases.

SAFER Detection For Efficient Interrogation Of DNA Rearrangements

Learn about SAFER Detection, a Next-Generation Sequencing (NGS) based method for the efficient identification of DNA rearrangements in gene-edited human cells.

A Toolkit For Unraveling Protein Expression Patterns

Learn about a method that utilizes monoclonal antibodies and flow cytometry to analyze the metabolic state of individual immune cells, advancing immune research and immunotherapy.

Study Viral Infection In Resting Humans CD4+ T Cells With Synthetic sgRNAs

Discover how Synthego's proprietary synthetic sgRNA, combined with Lonza’s 4D-Nucleofector®, enabled highly efficient gene editing in resting human CD4+ T cells.

SPONSOR

10% Discount Code: CG10

Join the 10th Anniversary of the CAR-TCR Summit to reflect on a decade of progress whilst engaging in solutions-driven discussions that will empower you to tackle cell therapy development challenges to help shape the future of the field. You’re guaranteed to leave with actionable solutions to combat the challenges currently halting your therapeutic development and effectively translate your cell therapy from bench to bedside.

TRANSLATIONAL RESEARCH SOLUTIONS

Organ On A Chip: Advancing New Approach Methodologies - Battelle

Be Unstoppable With Comprehensive Charge Variant Analysis - Danaher Life Sciences

EVENTS

Advancing the Future of Cell & Gene Therapy

This 11-12 November, Cell 2025 unites 1,000+ leading experts across the CGT value chain to solve key challenges, from scalable bioprocessing and regulatory hurdles to accelerating development timelines.

 

Gain practical strategies across cell culture, therapy development, and CGT manufacturing, and hear from world-renowned leaders Bobby Gaspar (CEO, Orchard Therapeutics), Christof Von Kalle, (Director & BIH Chair, Research Clinic Luxemburg), and Dame Molly Stevens (University of Oxford). Register Now

Connect With Cell & Gene: