Newsletter | September 2, 2026

09.02.26 -- Engineering Tregs To Target Solid Tumors With CoRegen's Dr. Sonal Gupta

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Reimagining Solid Tumor Immunotherapy Through Engineered Tregs with CoRegen's Dr. Sonal Gupta

In Episode 135 of Cell & Gene: The Podcast, Host Erin Harris talks to Sonal Gupta, MD, Ph.D., Chief Medical Officer of CoRegen, about the company's novel approach to treating solid tumors by engineering regulatory T cells (Tregs) rather than conventional effector immune cells.

 

 

Where Is T Cell Immunotherapy Headed Next For Your Pipeline Strategy?

CAR-T therapies drive 73% of active pipeline programs, yet solid tumors remain out of reach. Explore what the next wave of progress means for your strategy.

 

In-Line Monitoring Of Culture Medium Using Live Cell Metabolic Analyzer

See how continuous in-line monitoring of glucose and lactate levels provides highly accurate, real-time data on cellular metabolism without the risks or data gaps associated with manual periodic sampling.

 

Compressing Your CAR-T Optimization Timeline With Electroporation

Discover how high-throughput electroporation screening compresses CAR-T optimization timelines while delivering reproducible, scale-ready results across donors.

 

Determining The Linear Range For Quantitative Western Blot Detection

Learn how to determine the linear range for western blot quantification using total protein stains or housekeeping proteins to ensure accurate normalization and avoid saturation effects.

 

Modeling Neurodegenerative Disorders: Where Are We Now?

Neurodegenerative disease research faces a critical gap between symptom management and disease modification, making better preclinical models an urgent priority for the field.

 

Bridging Discovery And CMC With Rapid Pools

Early stable CHO expression data reveal manufacturability issues in complex antibodies that transient screening misses, with case studies showing how this changes lead selection.

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