Determining Viral Titre – A Critical Parameter During Lentiviral Vector Manufacture

In previous posts on lentiviral vector (LVV) manufacturing, we provided a general overview of the process with a focus on the scale-up of upstream and downstream processing. Here, we introduce the concept of analytics for LVV manufacture with a discussion of the basic assays used to determine the quantity of virus that is being produced.

This article explores quality control assays for LVV manufacture and improving assays for LVV production.