01.22.25 -- CTMC's 2025 Cell Therapy Manufacturing Outlook

Determination of biodistribution in both the preclinical and early clinical phases is an essential aspect of developing these novel therapies.

Learn how this Blood Vessel-Chip is capable of replicating drug side effects and mimicking the human circulatory system accurately, enhancing drug safety and efficacy in development.

Explore the significance of low-shear separation and delve into the principles of tubular bowl centrifugation, comparing it to alternative technologies.

CRISPR therapies are being developed for genetic disorders, cancer, and infectious diseases. Explore which CRISPR clinical trials are worth keeping an eye on this year.

Delve into the intricacies of riboswitch behavior and ligand interactions and gain valuable insights into gene regulation and potential therapeutic targets.

AI-driven multiplexed imaging reveals neuroimmune interactions in Alzheimer’s disease, identifying immune cell subtypes near pathological hallmarks like Β-amyloid plaques offering therapeutic insights.

In this study, a fully automated workflow utilizing the BD FACSDuet™ Premium Sample Preparation System integrated with the BD FACSLyric™ Flow Cytometer was assessed.

Learn about the effectiveness of a xeno-free serum replacement in mesenchymal stem cell (MSC) culture and its potential to enhance cell growth and reduce variability compared to fetal bovine serum.

What is mass photometry and how is it used? Explore this powerful analytical technology that measures the mass of single particles in solution accurately and without labels.

Explore the use of a mini bioreactor system for stem cell culturing that optimized process parameters of a human induced pluripotent stem cell (hiPSC) culture in a step-by-step process.

Sickle cell patients face limited access to effective treatments. Advocacy groups are pushing for greater awareness of innovative therapies like apheresis to improve outcomes and address resource gaps.

When it comes to process development, timing, technology, and partners all merit careful consideration. Explore expert insights into these three crucial factors.