Corning® Matribot® Bioprinter: An Easy-To-Use Tool For 3D Cell Culture

By Zhang Linyu and Chen Rui

Bioprinting technology has grown along with stem cell research and has become a vital tool with diverse applications in the biological and medical fields. In vitro 3D cell culture techniques create an accurate in vitro environment and provide an alternative to in vivo models used for fundamental cell biology and physiology research. However, these applications are currently hampered by organoid variability, low throughput, and limited scale. Although bioprinting technology is expected to be applied in regenerative medicine and drug discovery, there are enduring concerns regarding the impact of cell dispensers on cell integrity.

The Corning Matribot bioprinter exhibited cell-friendly dispensing performance similar to that of the manual dispensing operation. The culture dispensed by the Corning Matribot bioprinter were suitable for further molecular and protein analysis as well as downstream applications including high throughput drug screening.