Newsletter | March 25, 2025

03.25.25 -- Collaboration Leads To CGT Progress At Astellas' West Coast Innovation Center

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Introducing a new way to source solutions for improving, refining, and optimizing your CGT manufacturing! From April 8-10, Life Science Connect brings you the next virtual showcase from its network of trusted communities: Cell & Gene Therapy Tech Expo. Simply bring your attention, questions, and manufacturing requirements (no travel, cost, or inconvenience!) and experience this unique opportunity to learn about the latest technologies in CGT manufacturing and how they can help solve your biggest challenges.

FOCUS ON MANUFACTURING

Collaboration Leads To CGT Progress At Astellas' West Coast Innovation Center

Yoshi Shitaka, outgoing CSO and Richard Wilson, SVP, Primary Focus Lead (Genetic Regulation) at Astellas share how the company's West Coast Innovation Center serves as a central hub for AI.

Considerations For Cell Therapy Development And Manufacturing

Review the latest methodologies, common practices, resources, applications and more to support every step of your cell therapy manufacturing workflow.

Design Verification Testing Of Combination Products

Developing a combination product and seeking a list of tests to complete design verification testing? Review the details for planning, design inputs, design outputs, and design verification.

EVs Answer To The CAR-Tease: Targeted Exosomes

Researchers are exploring extracellular vesicles to deliver CARs, potentially offering safer, more accessible, and effective treatments compared to current CAR-T cell therapies.

Scale-Up Of Pluripotent Stem Cells In Vertical-Wheel Bioreactors

Discover the key requirements for efficient and linear scale-up of shear-sensitive pluripotent stem cell and other cell therapy products using the Vertical-Wheel bioreactor family.

Aseptic Filling Solution Enhances Sterility Assurance for Pharma Manufacturer

Emergent BioSolutions upgraded its Winnipeg site with the Cytiva SA25 aseptic filling workcell to improve sterility assurance, product flexibility, and regulatory compliance for CGT manufacturing.

Key Elements For An Improved CAR-T Therapy

Watch to learn about a new serum-free T cell media designed to overcome the barriers hindering CAR-T therapies and explore the importance of transduction efficiency in CAR T-cell therapy.

Tips For Designing A Single-Use Manifold For Advanced Therapies

Expert single-use engineers address six common questions posed by cell and gene therapy manufacturers in the design of custom single-use manifolds for the critical handling of biological fluids.

How Automation And AI Can Accelerate Clinical Research And Outbreak Response

Explore AI-driven automation and organ-on-a-chip technology to accelerate infectious disease research, improving vaccine and therapeutic development for emerging global health threats.

Isolation Of Antigen Specific CD8+ T Cells Using A Microchip-Based Cell Sorter

Here, we demonstrate the capacity of a specific bench top sorter to allow for completely aseptic sorting conditions by using the system to sort cancer antigen-specific cytotoxic T cells out of PBMCs.

MANUFACTURING SOLUTIONS

AAV Analytics With Mass Photometry - Refeyn

Efficient Production Of MSCs And Exosomes - Terumo BCT

Nuvia wPrime 2A Media - Bio-Rad Laboratories, Inc.

High-Performance Delivery Of Molecules With Minimal Disturbance - MaxCyte, Inc.

A Comprehensive Upstream Platform For Gene Therapy Applications - Cytiva

Single-Use Vessels For Cell Culture - Eppendorf SE

Cell And Gene Therapy Complete Contamination Control Strategy - Ecolab Life Sciences

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